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APOC3 / Apolipoprotein C III

apolipoprotein C-III

Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion; extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors.

Gene Name: apolipoprotein C-III
Synonyms: APOC3, Apo-CIII, Apolipoprotein C3, APOCIII, HALP2, ApoC-III, Apolipoprotein C-III
Target Sequences: NM_000040 NP_000031.1 P02656

Publications (2)

1
Development of a sensitive ELISA to quantify apolipoprotein CIII in nonhuman primate serum. Wang Y, Song Z, Wagner JD, Pachuk C, Subramanian RR. Journal of lipid research. 2011 52:1265-71. [PubMed:21371998] [PMC:PMC3090247]
2
Lowering apolipoprotein CIII protects against high-fat diet-induced metabolic derangements. Ismael Valladolid-Acebes, Karin Åvall, Patricia Recio-López, Noah Moruzzi, Galyna Bryzgalova, Marie Björnholm, Anna Krook, Elena Fauste Alonso, Madelene Ericsson, Fredrik Landfors, Stefan K Nilsson, Per-Olof Berggren, Lisa Juntti-Berggren. Science advances. 2021 March;7:eabc2931. [Full Text Article] [PubMed:33712458] [PMC:PMC7954448]

☰ Filters
Products
Proteins (13)
Over-Expression Lysate (2)
Recombinant (11)
APOC3 / Apolipoprotein C III (13)
No (13)
6His-SUMO, N-terminus (2)
GST, N-terminus (2)
His (2)
His, N-Terminal (1)
His-GST (1)
His-SUMO (1)
MBP, N-terminus + 6His, C-terminus (1)
Myc-DDK (Flag) (3)
Crab-eating macaque (2)
Human (6)
Mouse (2)
Rat (2)
293T Cells (1)
Baculovirus (1)
E. coli (5)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Yeast (2)
Purified (3)
APOC3 / Apolipoprotein C III Protein - Recombinant Apolipoprotein C3 By SDS-PAGE
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E. coli
His, N-Terminal
21 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
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E. coli
6His-SUMO, N-terminus
12.9 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
APOC3 / Apolipoprotein C III Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Yeast
6His-SUMO, N-terminus
100 µg/$446; 20 µg/$336; 1 mg/$1,460
APOC3 / Apolipoprotein C III Protein - Purified recombinant protein APOC3 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
8.7 kDa
20 µg/$1,107
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Wheat Germ Extract
GST, N-terminus
25 µg/$670; 10 µg/$479
APOC3 / Apolipoprotein C III Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
APOC3 / Apolipoprotein C III Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Baculovirus
MBP, N-terminus + 6His, C-terminus
100 µg/$1,164; 20 µg/$475; 1 mg/$2,187
APOC3 / Apolipoprotein C III Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
10.85 kDa
20 µg/$150
APOC3 / Apolipoprotein C III Protein - Recombinant Apolipoprotein C3 By SDS-PAGE
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E. coli
His
10.5 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,838
APOC3 / Apolipoprotein C III Protein - Recombinant Apolipoprotein C3 By SDS-PAGE
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E. coli
His-GST
40.7 kDa
10 µg/$268; 50 µg/$362; 100 µg/$577; 200 µg/$722; 1 mg/$1,755; 500 µg/$1,325; 5 mg/$2,708; 2 mg/$1,934
APOC3 / Apolipoprotein C III Protein
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Yeast
His
11 kD
100 µg/$499; 20 µg/$364; 1 mg/$1,683
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E. coli
His-SUMO
24.8 kD
1 mg/$1,679; 100 µg/$500; 20 µg/$364
APOC3 / Apolipoprotein C III Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
10.85 kDa
100 µg/$494
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).