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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
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APOBR / APOB48R
apolipoprotein B receptor
Macrophage receptor that binds to the apolipoprotein B48 (APOB) of dietary triglyceride (TG)-rich lipoproteins (TRL) or to a like domain of APOB in hypertriglyceridemic very low density lipoprotein (HTG-VLDL). Binds and internalizes TRL when out of the context of the macrophage. May provide essential lipids to reticuloendothelial cells. Could also be involved in foam cell formation with elevated TRL and remnant lipoprotein (RLP). Mediates the rapid high-affinity uptake of chylomicrons (CM), HTG-VLDL, and trypsinized (tryp) VLDL devoid of APOE in vitro in macrophages.
| Gene Name: | apolipoprotein B receptor |
| Synonyms: | APOBR, Apolipoprotein B-100 receptor, Apolipoprotein B48 receptor, APOB48R, ApoB-48R, Apolipoprotein B receptor, Apolipoprotein B-48 receptor, APOB100R, Apolipoprotein B100 receptor |
| Target Sequences: | NM_018690 NP_061160.3 Q0VD83 |
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