APOBEC3C

Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C

DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA. Exhibits antiviral activity against simian immunodeficiency virus (SIV), hepatitis B virus (HBV), herpes simplex virus 1 (HHV-1) and Epstein-Barr virus (EBV) and may inhibit the mobility of LTR and non-LTR retrotransposons. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.

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Products

Antibodies (29)

Proteins (6)

Type

Over-Expression Lysate (2)

Primary (29)

Recombinant (4)

Target

APOBEC3C (35)

Reactivity

Human (29)

Mouse (1)

Rat (2)

Application

IHC (6)

IHC-P (4)

WB (20)

Flo (1)

ELISA (12)

IF (2)

IP (8)

Peptide-ELISA (2)

Host

rabbit (21)

mouse (7)

goat (1)

Product Group

IHCPlus (2)

Isotype

Ig (1)

IgG (18)

IgG2a,k (6)

Clonality

monoclonal mc (6)

polyclonal pc (23)

Format

APC Conjugated (2)

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (2)

Unconjugated (19)

Epitope

aa1-190 (2)

C-Terminus (1)

N-Terminus (1)

aa201-212 (1)

aa91-191 (1)

Publications

No (34)

Yes (1)

Tag

GST (1)

GST, N-terminus (2)

Myc-DDK (Flag) (3)

Species

Human (5)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (2)

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IHC-plus™ APOBEC3C Antibody LS-B14538

(5.0) Rating

(1) Publication(s)

Antibody:

APOBEC3C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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APOBEC3C Antibody (aa1-190) LS-C380150

Antibody:

APOBEC3C Rabbit anti-Human Polyclonal (aa1-190) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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IHC-plus™ APOBEC3C Antibody LS-B11725

(4.0) Rating

Antibody:

APOBEC3C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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APOBEC3C Antibody (aa1-190) LS-C380151

Antibody:

APOBEC3C Rabbit anti-Human Polyclonal (aa1-190) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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APOBEC3C Antibody LS-C660064

Antibody:

APOBEC3C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

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APOBEC3C Antibody (aa201-212) LS-C112640

Antibody:

APOBEC3C Goat anti-Human Polyclonal (aa201-212) Antibody

Reactivity:

Human

Applications:

Flo, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

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APOBEC3C Antibody LS-C807437

Antibody:

APOBEC3C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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APOBEC3C Antibody (aa91-191) LS-C306295

Antibody:

APOBEC3C Mouse anti-Human Monoclonal (aa91-191) Antibody

Reactivity:

Human

Applications:

ELISA, IP

Format:

Unconjugated

Price:

100 µg/$705

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APOBEC3C Antibody (HRP) LS-C540902

Antibody:

APOBEC3C Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IP

Format:

HRP Conjugated

Price:

100 µl/$904

Select

APOBEC3C Antibody (Biotin) LS-C520769

Antibody:

APOBEC3C Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IP

Format:

Biotin Conjugated

Price:

100 µl/$904

Select

APOBEC3C Antibody (FITC) LS-C530813

Antibody:

APOBEC3C Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IP

Format:

FITC Conjugated

Price:

100 µl/$904

Select

APOBEC3C Antibody (APC) LS-C512554

Antibody:

APOBEC3C Mouse anti-Human Monoclonal (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IP

Format:

APC Conjugated

Price:

100 µl/$904

Select

APOBEC3C Antibody (PE) LS-C649014

Antibody:

APOBEC3C Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IP

Format:

PE Conjugated

Price:

100 µl/$904

• Unconjugated
• HRP
• Biotin
• FITC
• APC
• PE

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC
  • PE

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APOBEC3C Antibody LS-C779561

Antibody:

APOBEC3C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

APOBEC3C Antibody LS-C406132

Antibody:

APOBEC3C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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APOBEC3C Antibody (C-Terminus) LS-C758004

Antibody:

APOBEC3C Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$393

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APOBEC3C Antibody LS-C309473

Antibody:

APOBEC3C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µl/$749

Select

APOBEC3C Antibody LS-C749511

Antibody:

APOBEC3C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

APOBEC3C Antibody LS-C834318

Antibody:

APOBEC3C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

APOBEC3C Antibody LS-C334357

Antibody:

APOBEC3C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

APOBEC3C Antibody LS-C309472

Antibody:

APOBEC3C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$749

Select

APOBEC3C Antibody (Biotin) LS-C520768

Antibody:

APOBEC3C Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$937

• Unconjugated
• Biotin

• Unconjugated
• Biotin

Select

APOBEC3C Antibody (N-Terminus) LS-C354276

Antibody:

APOBEC3C Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299

Select

APOBEC3C Antibody LS-C833319

Antibody:

APOBEC3C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

APOBEC3C Antibody LS-C306291

Antibody:

APOBEC3C Mouse anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µg/$705

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