APOBEC1

Apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1

The apolipoprotein B mRNA editing protein (APOBEC1) is involved in the production of apolipoprotein B (apoB-)48 from apoB-100. APOBEC1 gene spans 18 kb and contains 5 exons, all of which are translated. The use of an alternative splice acceptor results in an alternative form APOBEC1 mRNA, which misses exon 2 causing a frameshift that produces a novel 36-amino acid peptide in which only the first 6-amino acids are shared with APOBEC1. The exon 2-skipped form accounts for approximately 50% of mRNA in the adult small intestine and up to 90% of APOBEC1 mRNA in the developing gut. Exon 2-skipping may thus be a quantitatively important mechanism regulating the expression on APOBEC1 in the gastrointestinal tract.

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

APOBEC1 (3)

Publications

No (3)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

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Human APOBEC1 Protein (Recombinant GST, N-terminus) (aa137-236) - LS-G57789

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human APOBEC1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74546

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

28 kDa

Price:

20 µg/$150

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APOBEC1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99504

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

28 kDa

Price:

100 µg/$494

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