Apg7 / ATG7

autophagy related 7

E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Modulates p53/TP53 activity to regulate cell cycle and survival during metabolic stress. Plays also a key role in the maintenance of axonal homeostasis, the prevention of axonal degeneration, the maintenance of hematopoietic stem cells, the formation of Paneth cell granules, as well as in adipose differentiation.

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Products

ELISA Kits (4)

Type

Sandwich (4)

Target

Apg7 / ATG7 (4)

Reactivity

Human (3)

Mouse (1)

Format

96-Well Strip Plate (4)

Publications

No (3)

Yes (1)

Sample Type

Cell Lysates (3)

Plasma (2)

Serum (2)

Tissue Homogenates (4)

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Mouse Apg7 / ATG7 (Sandwich ELISA) ELISA Kit - LS-F9293

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$923

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Human Apg7 / ATG7 (Sandwich ELISA) ELISA Kit - LS-F9291

(4.0) Rating

(1) Publication(s)

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$902

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Human Apg7 / ATG7 (Sandwich ELISA) ELISA Kit - LS-F51499

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

28 - 1800 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$958

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Human Apg7 / ATG7 (Sandwich ELISA) ELISA Kit - LS-F55852

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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