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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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APG12 / ATG12

autophagy related 12

Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. The ATG12-ATG5 conjugate also regulates negatively the innate antiviral immune response by blocking the type I IFN production pathway through direct association with RARRES3 and MAVS. Plays also a role in translation or delivery of incoming viral RNA to the translation apparatus.

Gene Name: autophagy related 12
Synonyms: ATG12, Autophagy-related protein 12, APG12L, Autophagy related 12, FBR93, APG12, APG12-like, Ubiquitin-like protein ATG12, HAPG12
Target Sequences: NM_004707 NP_004698.3 O94817

Publications (1)

1
Activation of autophagy in mesenchymal stem cells provides tumor stromal support. Sanchez CG, Penfornis P, Oskowitz AZ, Boonjindasup AG, Cai DZ, Dhule SS, Rowan BG, Kelekar A, Krause DS, Pochampally RR. Carcinogenesis. 2011 32:964-72. [PubMed:21317300] [PMC:PMC3128555] Related Antibodies: LS-C156569.

Filtered by: None
Target
APG12 / ATG12 (120)
Reactivity
Human (117)
Mouse (31)
Rat (24)
Bat (8)
Bovine (9)
Cat (1)
Chicken (9)
Chimpanzee (3)
Dog (9)
Donkey (1)
Goat (1)
Guinea pig (9)
Hamster (1)
Horse (9)
Monkey (10)
Orangutan (6)
Pig (9)
Rabbit (9)
Sheep (1)
Xenopus (8)
Yeast (1)
Zebrafish (8)
Application
IHC (42)
IHC-P (10)
WB (103)
ELISA (53)
ICC (14)
IF (62)
IP (12)
Host
rabbit (100)
mouse (18)
goat (1)
sheep (1)
Isotype
IgG (51)
IgG1,k (8)
IgG2b (7)
IgG2b,k (1)
Clonality
monoclonal mc (18)
polyclonal pc (102)
Clone
1F9 (1)
43CT73.3.5.5.4 (7)
Format
AP Conjugated (9)
APC Conjugated (8)
Atto 390 Conjugated (2)
Atto 488 Conjugated (2)
Atto 565 Conjugated (2)
Atto 594 Conjugated (4)
Atto 633 Conjugated (2)
Atto 655 Conjugated (2)
Atto 680 Conjugated (2)
Atto 700 Conjugated (2)
Azide-free (4)
Biotin Conjugated (11)
FITC Conjugated (11)
HRP Conjugated (11)
PE (2)
PE Conjugated (7)
PerCP Conjugated (2)
RPE Conjugated (2)
SA Conjugated (2)
Unconjugated (39)
Epitope
aa8-38 (8)
Ser26 (7)
aa26-56 (7)
N-Terminus (5)
C-Terminus (4)
aa79-128 (4)
Internal (1)
N-Terminal (1)
Ser129 (1)
aa1-30 (1)
internal region (1)
Publications
No (119)
Yes (1)
Showing 1-25 of 120 results

IHC-plus™ APG12 / ATG12 Antibody LS-B3216
Rabbit Polyclonal (IgG) to Human APG12 / ATG12
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50µg 1mg/ml  $545.00
Anti-ATG12 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-ATG12 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

APG12 / ATG12 Antibody (aa1-30) LS-C156569
Publications (1)
Publications (1)
Rabbit Polyclonal to Human APG12 / ATG12
Human
IF, IHC, IHC-P, WB
Unconjugated
400µl  $325.00
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with Autophagy APG12L antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

APG12 / ATG12 Antibody (C-Terminus) LS-C117261
Rabbit Polyclonal to Human APG12 / ATG12
Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey
WB
Unconjugated
100µl 0.5mg/ml  $365.00
ATG12 antibody Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

APG12 / ATG12 Antibody LS-C156567
Mouse Monoclonal (IgG2b,k) to Human APG12 / ATG12
Human
IF, IHC, IHC-P, WB
Unconjugated
400µl  $325.00
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue and lung carcinoma tissue reacted with APG12L Monoclonal Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with APG12L Monoclonal Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

IHC-plus™ APG12 / ATG12 Antibody (aa79-128) LS-B5897
Rabbit Polyclonal to Rat APG12 / ATG12
Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100µl  $485.00
Anti-ATG12 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
ATG12 antibody Western blot of Rat Kidney lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

APG12 / ATG12 Antibody (N-Terminus) LS-C69127
Rabbit Polyclonal (IgG) to Human APG12 / ATG12
Human
ELISA, IF, IP, WB
Unconjugated
100µl  $530.00

IHC-plus™ APG12 / ATG12 Antibody (Internal) LS-B2140
Rabbit Polyclonal (IgG) to Human APG12 / ATG12
Mouse, Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated
50µg 0.25mg/ml  $485.00
Anti-ATG12 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

APG12 / ATG12 Antibody LS-C126828
Rabbit Monoclonal (IgG) to Human APG12 / ATG12
Mouse, Rat, Human, Monkey
IP, WB
Unconjugated
100µl  $530.00

APG12 / ATG12 Antibody LS-C53240
Rabbit Polyclonal (IgG) to Human APG12 / ATG12
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
0.1mg 1mg/ml  $365.00
Immunohistochemistry of ATG12 in human brain tissue with ATG12 antibody at 2.5 µg/mL.
Immunofluorescence of ATG12 in Human Brain cells with ATG12 antibody at 20 ug/ml.

APG12 / ATG12 Antibody (clone 43CT73.3.5.5.4) LS-C319114
Mouse Monoclonal [clone 43CT73.3.5.5.4] (IgG2b) to Human APG12 / ATG12
Human
ELISA, IF, IHC, WB
Unconjugated
200µl  $590.00

APG12 / ATG12 Antibody (clone 43CT73.3.5.5.4, Biotin) LS-C232188
Mouse Monoclonal [clone 43CT73.3.5.5.4] (IgG2b) to Human APG12 / ATG12
Human
ELISA, ICC, IF, IHC, WB
Biotin Conjugated
200µl  $740.00

APG12 / ATG12 Antibody (clone 43CT73.3.5.5.4, FITC) LS-C232190
Mouse Monoclonal [clone 43CT73.3.5.5.4] (IgG2b) to Human APG12 / ATG12
Human
ELISA, ICC, IF, IHC, WB
FITC Conjugated
200µl  $740.00

APG12 / ATG12 Antibody (clone 43CT73.3.5.5.4, AP) LS-C232186
Mouse Monoclonal [clone 43CT73.3.5.5.4] (IgG2b) to Human APG12 / ATG12
Human
ELISA, ICC, IF, IHC, WB
AP Conjugated
200µl  $740.00

APG12 / ATG12 Antibody (clone 43CT73.3.5.5.4, APC) LS-C232189
Mouse Monoclonal [clone 43CT73.3.5.5.4] (IgG2b) to Human APG12 / ATG12
Human
ELISA, ICC, IF, IHC, WB
APC Conjugated
200µl  $740.00

APG12 / ATG12 Antibody (clone 43CT73.3.5.5.4, PE) LS-C232191
Mouse Monoclonal [clone 43CT73.3.5.5.4] (IgG2b) to Human APG12 / ATG12
Human
ELISA, ICC, IF, IHC, WB
PE Conjugated
200µl  $740.00

APG12 / ATG12 Antibody (clone 43CT73.3.5.5.4, Azide-free, HRP) LS-C249330
Mouse Monoclonal [clone 43CT73.3.5.5.4] (IgG2b) to Human APG12 / ATG12
Human
ELISA, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200µl  $740.00

APG12 / ATG12 Antibody (N-Terminus) LS-C69126
Rabbit Polyclonal (IgG) to Mouse APG12 / ATG12
Mouse
ICC, IF, IP, WB
Unconjugated
100µl  $530.00

APG12 / ATG12 Antibody (aa8-38, Biotin) LS-C243701
Rabbit Polyclonal (IgG) to Human APG12 / ATG12
Mouse, Human
ELISA, ICC, IF, WB
Biotin Conjugated
200µl  $740.00

APG12 / ATG12 Antibody (aa8-38, FITC) LS-C243702
Rabbit Polyclonal (IgG) to Human APG12 / ATG12
Mouse, Human
ELISA, ICC, IF, WB
FITC Conjugated
200µl  $740.00

APG12 / ATG12 Antibody (aa8-38, AP) LS-C243699
Rabbit Polyclonal (IgG) to Human APG12 / ATG12
Mouse, Human
ELISA, ICC, IF, WB
AP Conjugated
200µl  $740.00

APG12 / ATG12 Antibody (aa8-38, APC) LS-C243700
Rabbit Polyclonal (IgG) to Human APG12 / ATG12
Mouse, Human
ELISA, ICC, IF, WB
APC Conjugated
200µl  $740.00

APG12 / ATG12 Antibody (aa8-38, PE) LS-C243705
Rabbit Polyclonal (IgG) to Human APG12 / ATG12
Mouse, Human
ELISA, ICC, IF, WB
PE Conjugated
200µl  $740.00

APG12 / ATG12 Antibody (aa8-38, Azide-free, HRP) LS-C247443
Rabbit Polyclonal (IgG) to Human APG12 / ATG12
Mouse, Human
ELISA, ICC, IF, WB
HRP Conjugated, Azide-free
200µl  $740.00

APG12 / ATG12 Antibody LS-C659268
Rabbit Polyclonal (IgG) to Human APG12 / ATG12
Human
ELISA, IHC, IP, WB
Unconjugated
100µg  $435.00

APG12 / ATG12 Antibody LS-C659269
Rabbit Polyclonal (IgG) to Human APG12 / ATG12
Human
ELISA, IHC, IP, WB
Unconjugated
100µg  $405.00
Showing 1-25 of 120 results

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).