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APC6 / CDC16
cell division cycle 16
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
| Gene Name: | cell division cycle 16 |
| Synonyms: | CDC16, ANAPC6, APC6, CDC16 homolog, Cyclosome subunit 6, CDC16Hs, CUT9 |
| Target Sequences: | NM_003903 NP_003894.3 Q13042 |
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