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AP1G1 / Adaptin Gamma 1
adaptor-related protein complex 1, gamma 1 subunit
Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. Two transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | adaptor-related protein complex 1, gamma 1 subunit |
| Synonyms: | AP1G1, ADTG, AP-1 complex subunit gamma-1, CLAPG1, Gamma adaptin, Gamma1-adaptin |
| Target Sequences: | NM_001128 NP_001119.3 O43747 |
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