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Angiogenin / ANG
angiogenin, ribonuclease, RNase A family, 5
Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs). Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo.
| Gene Name: | angiogenin, ribonuclease, RNase A family, 5 |
| Synonyms: | ANG, Angiogenin, HEL168, ALS9, Ribonuclease 5, RNASE5, Epididymis luminal protein 168, RNase 5 |
| Target Sequences: | NM_001145 NP_001136.1 P03950 |
Publications (2)
1
Differential gene expression in normal esophagus and Barrett's esophagus. Wang J, Qin R, Ma Y, Wu H, Peters H, Tyska M, Shaheen NJ, Chen X. Journal of gastroenterology. 2009 44:897-911. (IHC-P; Human)
[PubMed:19468668]
2
Prostate cancer-derived angiogenin stimulates the invasion of prostate fibroblasts. Jones ML, Ewing CM, Isaacsa WB, Getzenberg RH. Journal of cellular and molecular medicine. 2012 16:193-201. (WB; Human)
[Full Text Article]
[PubMed:21352472]
Related Antibodies: LS-C34969.
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Angiogenin / ANG Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$545
Angiogenin / ANG Goat anti-Human Polyclonal Antibody
Human
ELISA, Neut, WB
Unconjugated
100 µg/$832
Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
E. coli
6His, N-terminus
15.8 kDa
10 µg/$283; 50 µg/$452; 100 µg/$725; 200 µg/$905; 1 mg/$2,020; 500 µg/$1,558; 5 mg/$3,165; 2 mg/$2,209
Angiogenin / ANG Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
Angiogenin / ANG Rabbit anti-Mouse Polyclonal (aa25-145) Antibody
Mouse
WB
Unconjugated
100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535; 2 ml/$698; 5 ml/$1,161
E. coli
6His, N-terminus
15.3 kDa
10 µg/$278; 50 µg/$422; 100 µg/$677; 200 µg/$845; 1 mg/$1,938; 500 µg/$1,485; 5 mg/$2,955; 2 mg/$2,124
Sandwich
96-Well Microplate
Rat
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$626
Angiogenin / ANG Rabbit anti-Bovine Polyclonal (HRP) Antibody
Bovine
ELISA, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
Sandwich
96-Well Microplate
Pig
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$627
E. coli
6His, N-terminus
14 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365
Sandwich
96-Well Strip Plate
Human
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Angiogenin / ANG Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
Angiogenin / ANG Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
Angiogenin / ANG Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
Angiogenin / ANG Rabbit anti-Human Polyclonal (aa27-147) (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Angiogenin / ANG Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
Angiogenin / ANG Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
Angiogenin / ANG Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$321
Angiogenin / ANG Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Angiogenin / ANG Mouse anti-Human Monoclonal (Preservative Free) (5B12-F10-E7) Antibody
Human
ELISA, WB
Unconjugated, Preservative Free
20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452
Angiogenin / ANG Mouse anti-Human Monoclonal (Preservative Free) (Biotin) (5B12-F10-E7) Antibody
Human
ELISA, WB
Biotin Conjugated, Preservative Free
50 µg/$343
Angiogenin / ANG Mouse anti-Human Monoclonal (2A7) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
Angiogenin / ANG Mouse Monoclonal (MANG-1) Antibody
Human
IHC, IHC-P
Unconjugated
150 µg/$728
Angiogenin / ANG Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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