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ANAPC11 / APC11

anaphase promoting complex subunit 11

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.

Gene Name: anaphase promoting complex subunit 11
Synonyms: ANAPC11, Apc11p, APC11, Cyclosome subunit 11, HSPC214
Target Sequences: NM_016476 NP_057560.8 Q9NYG5

Publications (2)

1
Association with cullin partners protects ROC proteins from proteasome-dependent degradation. Ohta T, Michel JJ, Xiong Y. Oncogene. 1999 18:6758-66. [PubMed:10597284] Related Antibodies: LS-C19022.
2
Activation of UBC5 ubiquitin-conjugating enzyme by the RING finger of ROC1 and assembly of active ubiquitin ligases by all cullins. Furukawa M, Ohta T, Xiong Y. The Journal of biological chemistry. 2002 277:15758-65. [PubMed:11861641] Related Antibodies: LS-C19022.

☰ Filters
Products
Proteins (17)
Over-Expression Lysate (14)
Recombinant (3)
ANAPC11 / APC11 (17)
No (17)
GST (1)
His, N-Terminal (1)
Myc-DDK (Flag) (15)
Human (10)
293T Cells (7)
E. coli (1)
HEK 293 Cells (8)
Wheat Germ Extract (1)
Purified (1)
ANAPC11 / APC11 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
9.7 kDa
100 µg/$494
ANAPC11 / APC11 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
9.7 kDa
100 µg/$494
ANAPC11 / APC11 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
20.5 kDa
100 µg/$494
ANAPC11 / APC11 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
9.7 kDa
100 µg/$494
ANAPC11 / APC11 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
9.7 kDa
100 µg/$494
ANAPC11 / APC11 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
9.7 kDa
100 µg/$494
ANAPC11 / APC11 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
9.7 kDa
100 µg/$494
ANAPC11 / APC11 Protein
Select
E. coli
His, N-Terminal
9.7 kDa
50 µg/$419
ANAPC11 / APC11 Protein - 12.5% SDS-PAGE of human ANAPC11 stained with Coomassie Blue
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Wheat Germ Extract
GST
31.68 kDa
10 µg/$479; 25 µg/$670
ANAPC11 / APC11 Protein - Purified recombinant protein ANAPC11 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
20.5 kDa
20 µg/$1,107
Select
293T Cells
Myc-DDK (Flag)
20.5 kDa
20 µg/$150
ANAPC11 / APC11 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
9.7 kDa
20 µg/$150
ANAPC11 / APC11 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
9.7 kDa
20 µg/$150
ANAPC11 / APC11 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
9.7 kDa
20 µg/$150
ANAPC11 / APC11 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
9.7 kDa
20 µg/$150
ANAPC11 / APC11 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
9.7 kDa
20 µg/$150
ANAPC11 / APC11 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
9.7 kDa
20 µg/$150
Viewing 1-17 of 17 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).