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ANAPC11 / APC11

anaphase promoting complex subunit 11

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.

Gene Name: anaphase promoting complex subunit 11
Synonyms: ANAPC11, Apc11p, APC11, Cyclosome subunit 11, HSPC214
Target Sequences: NM_016476 NP_057560.8 Q9NYG5

Publications (2)

1
Association with cullin partners protects ROC proteins from proteasome-dependent degradation. Ohta T, Michel JJ, Xiong Y. Oncogene. 1999 18:6758-66. [PubMed:10597284] Related Antibodies: LS-C19022.
2
Activation of UBC5 ubiquitin-conjugating enzyme by the RING finger of ROC1 and assembly of active ubiquitin ligases by all cullins. Furukawa M, Ohta T, Xiong Y. The Journal of biological chemistry. 2002 277:15758-65. [PubMed:11861641] Related Antibodies: LS-C19022.

☰ Filters
Antibodies (25)
Proteins (17)
Over-Expression Lysate (14)
Primary (25)
Recombinant (3)
ANAPC11 / APC11 (42)
Human (25)
Mouse (2)
Rat (1)
IHC (13)
IHC-P (6)
WB (25)
Flo (1)
ELISA (12)
IF (11)
IP (1)
rabbit (5)
mouse (20)
Product Group
IHCPlus (1)
Ig (1)
IgG (3)
IgG1 (12)
IgG1,k (6)
IgG2a (2)
monoclonal mc (20)
polyclonal pc (5)
1B4-1A4 (1)
6F1G9 (1)
6F1H6 (1)
OTI1A8 (2)
OTI1B11 (2)
OTI1B5 (2)
OTI1F2 (2)
OTI3C4 (2)
OTI3F5 (2)
APC Conjugated (1)
Biotin Conjugated (1)
Carrier-free (6)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (20)
C-Terminus (1)
aa76-84 (1)
No (41)
Yes (1)
GST (1)
His, N-Terminal (1)
Myc-DDK (Flag) (15)
Human (10)
293T Cells (7)
E. coli (1)
HEK 293 Cells (8)
Wheat Germ Extract (1)
Purified (1)
ANAPC11 / APC11 Antibody - Anti-ANAPC11 / APC11 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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ANAPC11 / APC11 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$440
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ANAPC11 / APC11 Rabbit anti-Human Polyclonal (aa76-84) Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µl/$567
ANAPC11 / APC11 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-ANAPC11 mouse monoclonal antibody.
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ANAPC11 / APC11 Mouse anti-Human Monoclonal (OTI3F5) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
ANAPC11 / APC11 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-ANAPC11 mouse monoclonal antibody.
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ANAPC11 / APC11 Mouse anti-Human Monoclonal (Carrier-free) (OTI3F5) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
ANAPC11 / APC11 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-ANAPC11 mouse monoclonal antibody.
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ANAPC11 / APC11 Mouse anti-Human Monoclonal (OTI3C4) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
ANAPC11 / APC11 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-ANAPC11 mouse monoclonal antibody.
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ANAPC11 / APC11 Mouse anti-Human Monoclonal (Carrier-free) (OTI3C4) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
ANAPC11 / APC11 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-ANAPC11 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
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ANAPC11 / APC11 Mouse anti-Human Monoclonal (OTI1B11) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
ANAPC11 / APC11 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-ANAPC11 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
Select
ANAPC11 / APC11 Mouse anti-Human Monoclonal (Carrier-free) (OTI1B11) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
ANAPC11 / APC11 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-ANAPC11 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
Select
ANAPC11 / APC11 Mouse anti-Human Monoclonal (OTI1A8) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
ANAPC11 / APC11 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-ANAPC11 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
Select
ANAPC11 / APC11 Mouse anti-Human Monoclonal (Carrier-free) (OTI1A8) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
ANAPC11 / APC11 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-ANAPC11 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
Select
ANAPC11 / APC11 Mouse anti-Human Monoclonal (OTI1F2) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
ANAPC11 / APC11 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-ANAPC11 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
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ANAPC11 / APC11 Mouse anti-Human Monoclonal (Carrier-free) (OTI1F2) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
ANAPC11 / APC11 Antibody - Western blot analysis using ANAPC11 mAb against HEK293 (1) and ANAPC11 (AA: 1-196)-hIgGFc transfected HEK293 (2) cell lysate.
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ANAPC11 / APC11 Mouse anti-Human Monoclonal (6F1H6) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µl/$459
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ANAPC11 / APC11 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
ANAPC11 / APC11 Antibody - Western blot analysis using ANAPC11 mAb against HEK293 (1) and ANAPC11 (AA: 1-196)-hIgGFc transfected HEK293 (2) cell lysate.
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ANAPC11 / APC11 Mouse anti-Human Monoclonal (6F1G9) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$459
ANAPC11 / APC11 Antibody - Anti-ANAPC11 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ANAPC11.
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ANAPC11 / APC11 Mouse anti-Human Monoclonal (OTI1B5) Antibody
Human
IF, WB
Unconjugated
100 µl/$434
ANAPC11 / APC11 Antibody - Anti-ANAPC11 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ANAPC11.
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ANAPC11 / APC11 Mouse anti-Human Monoclonal (Carrier-free) (OTI1B5) Antibody
Human
IF, WB
Unconjugated, Carrier-free
100 µg/$511
Select
ANAPC11 / APC11 Mouse anti-Human Monoclonal (1B4-1A4) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$705
Select
ANAPC11 / APC11 Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$904
Select
ANAPC11 / APC11 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µl/$904
Select
ANAPC11 / APC11 Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
100 µl/$904
Select
ANAPC11 / APC11 Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, WB
PE Conjugated
100 µl/$904
Select
ANAPC11 / APC11 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, WB
APC Conjugated
100 µl/$904
ANAPC11 / APC11 Antibody - All lanes: Anti-ANAPC11 Antibody (C-Term) at 1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: PC-3 whole cell lysate Lane 3: T47D whole cell lysate Lane 4: U-2OS whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size: 10 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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ANAPC11 / APC11 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$393
ANAPC11 / APC11 Antibody - Western blot analysis of extracts of mouse heart, using ANAPC11 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 120s.
Select
ANAPC11 / APC11 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Viewing 1-25 of 42 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).