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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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AMICA / JAML

adhesion molecule, interacts with CXADR antigen 1

Transmembrane protein of the plasma membrane of leukocytes that control their migration and activation through interaction with CXADR, a plasma membrane receptor found on adjacent epithelial and endothelial cells. The interaction between both receptors mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, AMICA1 induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair. It also controls the transmigration of leukocytes within epithelial and endothelial tissues through adhesive interactions with epithelial and endothelial CXADR.

Gene Name: adhesion molecule, interacts with CXADR antigen 1
Synonyms: AMICA1, AMICA, CREA7-1, CREA7-4, Adhesion molecule AMICA, Gm638, Junctional adhesion molecule, JAML
Target Sequences: NP_694938.2 Q86YT9

Viewing 1-25 of 28 items
AMICA / JAML Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Rabbit Polyclonal to Human AMICA / JAML
Human
IHC, IHC-P, WB
Unconjugated
200µl   $425.00
AMICA / JAML Antibody - Western blot of Human MCF7. AMICA1 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human AMICA / JAML
Human
WB
Unconjugated
100µl   0.5mg/ml   $365.00
Select
Mouse Monoclonal [clone 401901] (IgG2a) to Human AMICA / JAML
Human
ELISA, Flo, WB
Unconjugated
100µg   $650.00
Select
Goat Polyclonal (IgG) to Human AMICA / JAML
Human
ELISA, Flo, WB
Unconjugated
100µg   $785.00
Select
Mouse Monoclonal [clone 7H215] (IgG2b) to Human AMICA / JAML
Human
ELISA, WB
Unconjugated
100µg   $650.00
Select
Rabbit Polyclonal (IgG) to Human AMICA / JAML
Human
ELISA, WB
Unconjugated
200µl   0.47mg/ml   $590.00
Select
Rabbit Polyclonal (IgG) to Human AMICA / JAML
Human
ELISA, WB
Biotin Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human AMICA / JAML
Human
ELISA, WB
FITC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human AMICA / JAML
Human
ELISA, WB
AP Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human AMICA / JAML
Human
ELISA, WB
APC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human AMICA / JAML
Human
ELISA, WB
PE Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human AMICA / JAML
Human
ELISA, WB
HRP Conjugated, Azide-free
200µl   $740.00
AMICA / JAML Antibody
Select
Rabbit Polyclonal to Human AMICA / JAML
Human
ELISA, WB
Unconjugated
100µg   $275.00
Select
Rabbit Polyclonal (IgG) to Human AMICA / JAML
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100µg   $335.00
AMICA / JAML Antibody - 1:100 staining human liver carcinoma tissues by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
Rabbit Polyclonal (IgG) to Human AMICA / JAML
Human
ELISA, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
AMICA / JAML Antibody - Staining of mouse JAML-transfected CHO cells with 0.5 ug of Purified Armenian Hamster IgG isotype control (open histogram) or 0.5 ug of Purified anti-mouse JAML (4E10) (colored histogram) followed by FITC Anti-Armenian Hamster IgG. Total viable cells were used for analysis.
Select
Hamster Monoclonal [clone 4E10] (IgG) to Mouse AMICA / JAML
Mouse
Flo, IP
Unconjugated
50µg   $245.00; 100µg   $305.00; 500µg   $455.00
Select
Rabbit Polyclonal to Human AMICA / JAML
Human
ELISA, WB
Unconjugated
100µg   100µl   1mg/ml   $305.00
Select
Mouse Monoclonal to Human AMICA / JAML
Human
ELISA
Unconjugated
50µl   $235.00; 100µl   $275.00; 200µl   $305.00
Select
Mouse Monoclonal [clone 05] (IgG) to Human AMICA / JAML
Human
ELISA
Unconjugated, Preservative Free
50µl   $235.00; 100µl   $275.00; 200µl   $305.00; 1ml   $995.00
Select
Mouse Monoclonal [clone 06] (IgG) to Human AMICA / JAML
Human
ELISA
Unconjugated, Preservative Free
50µl   $235.00; 100µl   $275.00; 200µl   $305.00; 1ml   $995.00
Select
Goat Polyclonal (IgG) to Human AMICA / JAML
Human
ELISA, WB
Biotin Conjugated
50µg   $860.00
Select
Rabbit Polyclonal (IgG) to Human AMICA / JAML
Human
ELISA
Unconjugated, Preservative Free
50µl   $235.00; 100µl   $275.00; 200µl   $305.00
Select
Rabbit Polyclonal (IgG) to Human AMICA / JAML
Human
ELISA
Unconjugated, Preservative Free
100µl   $235.00; 200µl   $275.00; 400µl   $305.00
Select
Rabbit Polyclonal (IgG) to Human AMICA / JAML
Rat, Human
WB
Unconjugated
50µl   $235.00; 100µl   $295.00; 200µl   $385.00
Select
Mouse Polyclonal (IgG) to Human AMICA / JAML
Human
WB
Unconjugated
50µg   $560.00

Viewing 1-25 of 28 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).