Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Homo sapiens S-adenosylmethionine decarboxylase 1 (AMD1)is an important intermediate enzyme in polyamine biosynthesis. The polyamines spermine, spermidine, and putrescine are low-molecular-weight aliphatic amines essential for cellular proliferation and tumor promotion. An AMD pseudogene, AMD2, is found on chromosome X. The AMD1 gene spans 22 kb comprised of 9 exons and 8 introns and encoding two species of mRNA of 2.1 and 3.4-3.6 kb originating from the use of two different polyadenylation signals. The pro-protein is an approximate 38.3 kD which is known to undergo processing at amino acid 68 to yield two fragments of 32- and 6-kD.
|Gene Name:||adenosylmethionine decarboxylase 1|
|Synonyms:||AMD1, ADOMETDC, AMD, SAMDC|
|Target Sequences:||NM_001634 NP_001625.2 P17707|
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