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AMBP

alpha-1-microglobulin/bikunin precursor

Bikunin / AMBP is a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes.

Gene Name: alpha-1-microglobulin/bikunin precursor
Synonyms: AMBP, A1M, Alpha-1-microglobulin, Bikunin, HCP, IATIL, ITIL, HI30, ITI, ITILC, Protein AMBP, Uronic-acid-rich protein, UTI, Trypstatin, Uristatin, EDC1, Growth-inhibiting protein 19, Protein HC
Target Sequences: NM_001633 NP_001624.1 P02760

Publications (1)

1
Hepatokine a1-Microglobulin Signaling Exacerbates Inflammation and Disturbs Fibrotic Repair in Mouse Myocardial Infarction. Hakuno D, Kimura M, Ito S, Satoh J, Nakashima Y, Horie T, Kuwabara Y, Nishiga M, Ide Y, Baba O, Nishi H, Nakao T, Nishino T, Nakazeki F, Koyama S, Hanada R, Randolph RR, Endo J, Kimura T, Ono K. Scientific reports. 2018 November;8:16749. [Full Text Article] [PubMed:30425314] [PMC:PMC6233179] Related Antibodies: LS-C292739.

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).