Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

ALPL / Alkaline Phosphatase

alkaline phosphatase, liver/bone/kidney

There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants have been described.

Gene Name: alkaline phosphatase, liver/bone/kidney
Synonyms: ALPL, Alkaline phosphomonoesterase, AP-TNAP, Alkaline phosphatase liver, APTNAP, Glycerophosphatase, Tissue-nonspecific ALP, TNAP, HOPS, Liver alkaline phosphatase, TNSALP
Target Sequences: NM_000478 NP_000469.3 P05186

Publications (1)

1
Collagen-Hydroxyapatite Scaffolds Induce Human Adipose Derived Stem Cells Osteogenic Differentiation In Vitro. Calabrese G, Giuffrida R, Fabbi C, Figallo E, Lo Furno D, Gulino R, Colarossi C, Fullone F, Giuffrida R, Parenti R, Memeo L, Forte S. PloS one. 2016 11:e0151181. (WB, ELISA, IHC-Fr; Bovine, Human) [Full Text Article] [PubMed:26982592] [PMC:PMC4794180] Related Antibodies: LS-C98218.

☰ Filters
Products
ELISA Kits (25)
Competitive EIA (6)
Custom (1)
Sandwich (15)
Sandwich CLIA (3)
ALPL / Alkaline Phosphatase (25)
Human (6)
Mouse (6)
Rat (7)
Canine (1)
Chicken (1)
Monkey (1)
Pig (1)
Rabbit (1)
12 x 8-Well Microstrips (4)
96-Well Strip Plate (21)
No (25)
Cell Culture Supernatants (1)
Cell Supernatant (1)
Plasma (24)
Serum (24)
Tissue Homogenates (8)
ALPL / Alkaline Phosphatase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$818
ALPL / Alkaline Phosphatase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.5 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
ALPL / Alkaline Phosphatase ELISA Kit
Select
Sandwich
12 x 8-Well Microstrips
Human
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
ALPL / Alkaline Phosphatase ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Human
3.12 - 200 U/l
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
ALPL / Alkaline Phosphatase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
1.56 - 100 U/l
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$929
ALPL / Alkaline Phosphatase ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Mouse
0.5 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
ALPL / Alkaline Phosphatase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
3.12 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
ALPL / Alkaline Phosphatase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
ALPL / Alkaline Phosphatase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$856
ALPL / Alkaline Phosphatase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$798
ALPL / Alkaline Phosphatase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Supernatant, Plasma, Serum
1 Plate/$598
ALPL / Alkaline Phosphatase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Canine
0.469 - 30 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
ALPL / Alkaline Phosphatase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
0.156 - 10 mIU/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$870
ALPL / Alkaline Phosphatase ELISA Kit
Select
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$783
ALPL / Alkaline Phosphatase ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Rat
3.12 - 200 U/l
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
ALPL / Alkaline Phosphatase ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Rat
2.5 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
ALPL / Alkaline Phosphatase ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Rat
0.5 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
ALPL / Alkaline Phosphatase ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
15.625 - 1000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
ALPL / Alkaline Phosphatase ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Mouse
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
ALPL / Alkaline Phosphatase ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Rat
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
ALPL / Alkaline Phosphatase ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Mouse
1 - 25 U/l
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
ALPL / Alkaline Phosphatase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
ALPL / Alkaline Phosphatase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Pig
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
ALPL / Alkaline Phosphatase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
ALPL / Alkaline Phosphatase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$627
Viewing 1-25 of 25 product results


Filtered By:
Products: ELISA Kits


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).