ALOX15 / 15-Lipoxygenase

arachidonate 15-lipoxygenase

Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid into 12-hydroperoxyeicosatetraenoic acid/12-HPETE and 15-hydroperoxyeicosatetraenoic acid/15-HPETE. Also converts linoleic acid to 13-hydroperoxyoctadecadienoic acid. May also act on (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE to produce hepoxilin A3. Probably plays an important role in the immune and inflammatory responses. Through the oxygenation of membrane-bound phosphatidylethanolamine in macrophages may favor clearance of apoptotic cells during inflammation by resident macrophages and prevent an autoimmune response associated with the clearance of apoptotic cells by inflammatory monocytes. In parallel, may regulate actin polymerization which is crucial for several biological processes, including macrophage function. May also regulate macrophage function through regulation of the peroxisome proliferator activated receptor signaling pathway. Finally, it is also involved in the cellular response to IL13/interleukin-13. In addition to its role in the immune and inflammatory responses, may play a role in epithelial wound healing in the cornea maybe through production of lipoxin A4. May also play a role in endoplasmic reticulum stress response and the regulation of bone mass.

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Products

Antibodies (48)

Type

Primary (48)

Target

ALOX15 / 15-Lipoxygenase (48)

Reactivity

Human (48)

Mouse (12)

Rat (8)

Chimpanzee (3)

Dog (2)

Gibbon (3)

Monkey (6)

Orangutan (3)

Pig (3)

Rabbit (3)

Application

IHC (20)

IHC-P (8)

WB (47)

Flo (4)

ELISA (8)

ICC (1)

IF (6)

Peptide-ELISA (2)

Host

rabbit (25)

mouse (22)

goat (1)

Product Group

IHCPlus (3)

Isotype

IgG (18)

IgG2a (2)

IgG2a,k (6)

IgG2b (6)

Clonality

monoclonal mc (22)

polyclonal pc (26)

Clone

3D8 (1)

7H6 (2)

OTI2G3 (2)

OTI3G8 (2)

OTI8C5 (2)

Format

APC (2)

APC Conjugated (4)

Biotin Conjugated (5)

Carrier-free (4)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (5)

HRP Conjugated (5)

PE Conjugated (4)

Unconjugated (21)

Epitope

aa170-312 (16)

aa539-588 (4)

aa2-337 (1)

aa482-494 (1)

aa610-643 (1)

Publications

No (47)

Yes (1)

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IHC-plus™ ALOX15 / 15-Lipoxygenase Antibody (clone 3D8) LS-B4278

(4.0) Rating

Antibody:

ALOX15 / 15-Lipoxygenase Mouse anti-Human Monoclonal (3D8) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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ALOX15 / 15-Lipoxygenase Antibody (clone OTI2G3) LS-C173699

Antibody:

ALOX15 / 15-Lipoxygenase Mouse anti-Human Monoclonal (OTI2G3) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

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ALOX15 / 15-Lipoxygenase Antibody (clone OTI2G3, Carrier-free) LS-C786815

Antibody:

ALOX15 / 15-Lipoxygenase Mouse anti-Human Monoclonal (Carrier-free) (OTI2G3) Antibody

Reactivity:

Human

Applications:

Flo, IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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ALOX15 / 15-Lipoxygenase Antibody (aa610-643) LS-C99452

Antibody:

ALOX15 / 15-Lipoxygenase Rabbit anti-Human Polyclonal (aa610-643) Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$393

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ALOX15 / 15-Lipoxygenase Antibody (aa2-337) LS-C343940

Antibody:

ALOX15 / 15-Lipoxygenase Rabbit anti-Human Polyclonal (aa2-337) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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ALOX15 / 15-Lipoxygenase Antibody (aa170-312) LS-C292930

Antibody:

ALOX15 / 15-Lipoxygenase Rabbit anti-Human Polyclonal (aa170-312) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299; 200 µl/$337; 500 µl/$463; 1 ml/$527; 2 ml/$682; 5 ml/$1,141

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ALOX15 / 15-Lipoxygenase Antibody (aa170-312, Biotin) LS-C300672

Antibody:

ALOX15 / 15-Lipoxygenase Rabbit anti-Human Polyclonal (aa170-312) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$308; 200 µl/$350; 500 µl/$489; 1 ml/$558; 2 ml/$749; 5 ml/$1,217

• Unconjugated
• Biotin

• Unconjugated
• Biotin

Select

ALOX15 / 15-Lipoxygenase Antibody (aa539-588) LS-C111783

Antibody:

ALOX15 / 15-Lipoxygenase Rabbit anti-Human Polyclonal (aa539-588) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

IHC-plus™ ALOX15 / 15-Lipoxygenase Antibody (aa482-494) LS-B6689

(4.0) Rating

Antibody:

ALOX15 / 15-Lipoxygenase Goat anti-Human Polyclonal (aa482-494) Antibody

Reactivity:

Human, Monkey

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µg/$485

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ALOX15 / 15-Lipoxygenase Antibody (clone 7H6, Carrier-free) LS-C786937

Antibody:

ALOX15 / 15-Lipoxygenase Mouse anti-Human Monoclonal (Carrier-free) (7H6) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

Select

ALOX15 / 15-Lipoxygenase Antibody (clone OTI3G8) LS-C173722

Antibody:

ALOX15 / 15-Lipoxygenase Mouse anti-Human Monoclonal (OTI3G8) Antibody

Reactivity:

Dog, Rat, Human, Monkey

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$450

Select

ALOX15 / 15-Lipoxygenase Antibody (clone OTI3G8, Carrier-free) LS-C786848

Antibody:

ALOX15 / 15-Lipoxygenase Mouse anti-Human Monoclonal (Carrier-free) (OTI3G8) Antibody

Reactivity:

Dog, Rat, Human, Monkey

Applications:

IF, IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

ALOX15 / 15-Lipoxygenase Antibody (aa170-312, Biotin) LS-C299109

Antibody:

ALOX15 / 15-Lipoxygenase Mouse anti-Human Monoclonal (aa170-312) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$314; 200 µl/$359; 500 µl/$506; 1 ml/$580; 2 ml/$797; 5 ml/$1,295

Select

ALOX15 / 15-Lipoxygenase Antibody (aa170-312, FITC) LS-C304832

Antibody:

ALOX15 / 15-Lipoxygenase Mouse anti-Human Monoclonal (aa170-312) (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$342; 200 µl/$399; 500 µl/$587; 1 ml/$725; 2 ml/$962; 5 ml/$1,647

• Biotin
• FITC

• Biotin
• FITC

Select

ALOX15 / 15-Lipoxygenase Antibody LS-C659218

Antibody:

ALOX15 / 15-Lipoxygenase Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

ALOX15 / 15-Lipoxygenase Antibody (HRP) LS-C543422

Antibody:

ALOX15 / 15-Lipoxygenase Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated

Price:

100 µl/$904

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ALOX15 / 15-Lipoxygenase Antibody (Biotin) LS-C523294

Antibody:

ALOX15 / 15-Lipoxygenase Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

100 µl/$904

Select

ALOX15 / 15-Lipoxygenase Antibody (FITC) LS-C533334

Antibody:

ALOX15 / 15-Lipoxygenase Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

100 µl/$904

Select

ALOX15 / 15-Lipoxygenase Antibody (APC) LS-C515037

Antibody:

ALOX15 / 15-Lipoxygenase Mouse anti-Human Monoclonal (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

100 µl/$904

Select

ALOX15 / 15-Lipoxygenase Antibody (PE) LS-C651532

Antibody:

ALOX15 / 15-Lipoxygenase Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

100 µl/$904

• HRP
• Biotin
• FITC
• APC
• PE

• HRP
• Biotin
• FITC
• More...
  • APC
  • PE

Select

ALOX15 / 15-Lipoxygenase Antibody LS-C349291

Antibody:

ALOX15 / 15-Lipoxygenase Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

ALOX15 / 15-Lipoxygenase Antibody LS-C667705

Antibody:

ALOX15 / 15-Lipoxygenase Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321

Select

ALOX15 / 15-Lipoxygenase Antibody (clone OTI8C5, Carrier-free) LS-C786846

Antibody:

ALOX15 / 15-Lipoxygenase Mouse anti-Human Monoclonal (Carrier-free) (OTI8C5) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

Select

ALOX15 / 15-Lipoxygenase Antibody LS-C406202

Antibody:

ALOX15 / 15-Lipoxygenase Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

ALOX15 / 15-Lipoxygenase Antibody LS-C803735

Antibody:

ALOX15 / 15-Lipoxygenase Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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