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ALK-6 / BMPR1B

bone morphogenetic protein receptor, type IB

ALK-6 / BMPR1B is a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene.

Gene Name: bone morphogenetic protein receptor, type IB
Family/Subfamily: Protein Kinase , Activin/TGFb
Synonyms: BMPR1B, Activin receptor-like kinase 6, ALK-6, Bmp receptor 1b, Bmp receptor ib, BMP receptor type IB, CDw293, CFK-43a, BMPR-1B, ALK6, Type IB BMPR, BMP type-1B receptor, BMPR-IB, CDw293 antigen, Type IB BMP receptor
Target Sequences: NM_001203 NP_001194.1 O00238

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Products
Proteins (8)
Over-Expression Lysate (2)
Recombinant (6)
ALK-6 / BMPR1B (8)
No (8)
Fc (1)
GST (1)
GST, N-terminus (2)
His (1)
His,N-terminus + GST (1)
Myc-DDK (Flag) (2)
Human (6)
Mouse (1)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Human Cells (1)
Insect Cells (1)
Wheat Germ Extract (3)
Purified (4)
Low endotoxin level (2)
ALK-6 / BMPR1B Protein
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E. coli
His
20 µg/$361; 100 µg/$739; 4 µg/$261
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Insect Cells
His,N-terminus + GST
Less than 1.0 EU/µg protein (determined by LAL method).
68.3 kDa
50 µg/$707
ALK-6 / BMPR1B Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
56.93 kDa
100 µg/$494
ALK-6 / BMPR1B Protein - 12.5% SDS-PAGE of human BMPR1B stained with Coomassie Blue
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Wheat Germ Extract
GST
79.53 kDa
2 µg/$439
ALK-6 / BMPR1B Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
ALK-6 / BMPR1B Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Select
Human Cells
Fc
Less than 1.0 EU/µg protein (determined by LAL method).
39.4 kDa
100 µg/$926
ALK-6 / BMPR1B Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
56.93 kDa
20 µg/$150
Viewing 1-8 of 8 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).