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ALDP / ABCD1

ATP-binding cassette, sub-family D (ALD), member 1

ALDP / ABCD1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system.

Gene Name: ATP-binding cassette, sub-family D (ALD), member 1
Family/Subfamily: Transporter , ATP-binding cassette - ABCD/ALD
Synonyms: ABCD1, ABC42, Adrenoleukodystrophy protein, ALD, Aldgh, Adrenoleukodystrophy, ALDP, X-ALD
Target Sequences: NM_000033 NP_000024.2 P33897

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Products
Proteins (7)
Over-Expression Lysate (2)
Recombinant (5)
ALDP / ABCD1 (7)
No (7)
10His, C-terminus (1)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (7)
293T Cells (1)
E. coli (2)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (3)
Biologically active (1)
ALDP / ABCD1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
82.8 kDa
100 µg/$494
ALDP / ABCD1 Protein - Purified recombinant protein ABCD1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
82.8 kDa
20 µg/$1,107
ALDP / ABCD1 Protein - Recombinant ATP Binding Cassette Transporter D1 (ABCD1) by SDS-PAGE
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E. coli
None
62.1kDa
10 µg/$290; 50 µg/$500; 200 µg/$997; 100 µg/$797; 1 mg/$2,139; 500 µg/$1,662; 5 mg/$3,487; 2 mg/$2,329
ALDP / ABCD1 Protein - 12.5% SDS-PAGE of human ABCD1 stained with Coomassie Blue
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Wheat Germ Extract
GST
109.3 kDa
10 µg/$479; 25 µg/$670
ALDP / ABCD1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
82.8 kDa
20 µg/$150
ALDP / ABCD1 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
10His, C-terminus
Biologically active
100 µg/$2,335; 20 µg/$1,535
ALDP / ABCD1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Viewing 1-7 of 7 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).