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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ALDH2

aldehyde dehydrogenase 2 family (mitochondrial)

This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene Name: aldehyde dehydrogenase 2 family (mitochondrial)
Synonyms: ALDH2, Acetaldehyde dehydrogenase 2, ALDH-E2, ALDH class 2, ALDHI, ALDM, Liver mitochondrial ALDH
Target Sequences: NM_000690 NP_000681.2 P05091

Publications (1)

1
Comprehensive measurement of respiratory activity in permeabilized cells using extracellular flux analysis. Salabei JK, Gibb AA, Hill BG. Nature protocols. 2014 9:421-38. (ICC; Human) [Full Text Article] [PubMed:24457333] [PMC:PMC4063296]

Filtered by: None
Type
Over-Expression Lysate (2)
Recombinant (9)
Target
ALDH2 (11)
Tag
GST (2)
GST,N-terminus (1)
His (1)
His + S (1)
His, N-Terminal (2)
Myc + DDK (3)
Species
Human (8)
Mouse (2)
Source
293T Cells (1)
E. coli (6)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purification
Purified (7)
Low Endotoxin Level
Low endotoxin level (1)
Biologically Active
Biologically active (2)
Publications
No (11)
Showing 1-11 of 11 results

Human ALDH2 Protein (Recombinant) - LS-G486
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
100µg  $275.00; 0.5mg  $485.00
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

Mouse ALDH2 Protein (Recombinant His) - LS-G3318
E. coli
His
100µg 0.5mg/ml  $365.00; 0.5mg 0.5mg/ml  $935.00
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

Human ALDH2 Protein (Recombinant GST,N-terminus) (aa408-517) - LS-G57746
Wheat Germ Extract
GST,N-terminus
10µg  $425.00; 25µg  $590.00
12.5% SDS-PAGE Stained with Coomassie Blue.

Human ALDH2 Protein (Recombinant His + S) (aa59-150) - LS-G14643
E. coli
His + S
16.1 kDa
10µg  $225.00; 50µg  $315.00; 100µg  $375.00; 200µg  $465.00; 1mg  $1,185.00; 500µg  $530.00

Human ALDH2 Protein (Recombinant GST) - LS-G17620
E. coli
GST
Biologically active
10µg  $195.00; 50µg  $255.00; 1mg  $1,890.00

Human ALDH2 Protein (Recombinant GST) (Full Length) - LS-G27415
Wheat Germ Extract
GST
82.8 kDa
10µg  $425.00; 25µg  $590.00
12.5% SDS-PAGE of human ALDH2 stained with Coomassie Blue

Human ALDH2 Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G74399
293T Cells
Myc + DDK
56.38 kDa
20µg  $195.00

Human ALDH2 Protein (Recombinant Myc + DDK) (Full Length) - LS-G64883
HEK 293 Cells
Myc + DDK
54.4 kDa
20µg  $890.00
Purified recombinant protein ALDH2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining

Mouse ALDH2 Protein (Recombinant His, N-Terminal) (aa20-519) - LS-G134910
E. coli
His, N-Terminal
56.8kDa
5µg  $195.00; 20µg  $255.00; 1mg  $3,780.00

Human ALDH2 Protein (Recombinant His, N-Terminal) (Ser18-Ser517) - LS-G96747
E. coli
His, N-Terminal
57 kDa
10µg  $215.00; 100µg  $325.00; 250µg  $485.00; 50µg  $265.00
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

ALDH2 Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G99116
HEK 293 Cells
Myc + DDK
56.38 kDa
100µg  $365.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Showing 1-11 of 11 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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