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ALDH1L2
aldehyde dehydrogenase 1 family, member L2
ALDH1L2 encodes a member of both the aldehyde dehydrogenase superfamily and the formyl transferase superfamily. This member is the mitochondrial form of 10-formyltetrahydrofolate dehydrogenase (FDH), which converts 10-formyltetrahydrofolate to tetrahydrofolate and CO2 in an NADP(+)-dependent reaction, and plays an essential role in the distribution of one-carbon groups between the cytosolic and mitochondrial compartments of the cell. Alternatively spliced transcript variants have been found for this gene.
| Gene Name: | aldehyde dehydrogenase 1 family, member L2 |
| Synonyms: | ALDH1L2, MtFDH, Mitochondrial 10-FTHFDH |
| Target Sequences: | NM_001034173 NP_001029345.2 Q3SY69 |
Publications (2)
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