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B001/B101
Shirley, MA 01464
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20700 44th Avenue W
Lynnwood, WA 98036
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ALDH1A3
aldehyde dehydrogenase 1 family, member A3
Aldehyde dehydrogenase (ALDH) isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The gene for the human isozyme ALDH6 spans about 37 kb and consists of 13 exons. It is expressed at low levels in many tissues and at higher levels in salivary gland, stomach and kidney. The major transcript is approximately 3.5 kb however there is a less abundant transcript that is smaller by 111 bp in the 3' non-coding region and uses an alternative polyadenylation signal. The significance of alternative splicing of ALDH6 gene is currently unclear.
| Gene Name: | aldehyde dehydrogenase 1 family, member A3 |
| Synonyms: | ALDH1A3, Acetaldehyde dehydrogenase 6, ALDH6, Aldehyde dehydrogenase 6, ALDH1A6, RALDH3, Retinaldehyde dehydrogenase 3, RALDH-3 |
| Target Sequences: | NM_000693 NP_000684.2 P47895 |
Publications (1)
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