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ALDH1A1 / ALDH1

aldehyde dehydrogenase 1 family, member A1

ALDH1A1 / ALDH1 belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet.

Gene Name: aldehyde dehydrogenase 1 family, member A1
Synonyms: ALDH1A1, Acetaldehyde dehydrogenase 1, ALDH class 1, ALDC, Aldehyde dehydrogenase 1, ALDH-E1, ALDH1, ALDH11, PUMB1, RALDH 1, RALDH1, ALHDII, Retinal dehydrogenase 1, Retinaldehyde dehydrogenase 1
Target Sequences: NM_000689 NP_000680.2 P00352

Publications (3)

1
Targeting Breast Cancer Stem Cell State Equilibrium through Modulation of Redox Signaling. Ming Luo, Li Shang, Michael D Brooks, Evelyn Jiagge, Yongyou Zhu, Johanna M Buschhaus, Sarah Conley, Melissa A Fath, April Davis, Elizabeth Gheordunescu, Yongfang Wang, Ramdane Harouaka, Ann Lozier, Daniel Triner, Sean McDermott, Sofia D Merajver, Gary D Luker, Douglas R Spitz, Max S Wicha. Cell metabolism. 2018 July;28:69-86.e6. [Full Text Article] [PubMed:29972798] [PMC:PMC6037414]
2
BRCA1 mutation influences progesterone response in human benign mammary organoids. Batzaya Davaadelger, Mi-Ran Choi, Hari Singhal, Susan E Clare, Seema A Khan, J Julie Kim. Breast cancer research : BCR. 2019 Nov;21:124. [Full Text Article] [PubMed:31771627] [PMC:PMC6878650] Related Antibodies: LS-B10149.
3
Expanding the use of monoclonal antibody therapy of cancer by using ionising radiation to upregulate antibody targets. Wattenberg MM, Kwilas AR, Gameiro SR, Dicker AP, Hodge JW. British journal of cancer. 2014 Mar;110:1472-80. [Full Text Article] [PubMed:24556625] [PMC:PMC3960628] Related Antibodies: LS-B2497.

☰ Filters
Products
Proteins (14)
Over-Expression Lysate (2)
Recombinant (12)
ALDH1A1 / ALDH1 (14)
SDS-PAGE (1)
No (14)
6His, N-terminus (3)
GST (2)
GST, N-terminus (1)
His, N-Terminal (1)
His,N-terminus (1)
His-T7 (1)
His-T7, N-terminus (1)
Myc-DDK (Flag) (3)
Human (11)
Mouse (2)
293T Cells (1)
E. coli (7)
HEK 293 Cells (2)
Wheat Germ Extract (3)
Yeast (1)
Purified (5)
Low endotoxin level (2)
ALDH1A1 / ALDH1 Protein
Select
E. coli
None
100 µg/$342; 500 µg/$641; 20 µg/$254
ALDH1A1 / ALDH1 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Yeast
6His, N-terminus
1 mg/$1,973; 100 µg/$570; 20 µg/$395
ALDH1A1 / ALDH1 Protein
Select
E. coli
His,N-terminus
SDS-PAGE
The recombinant human ALDH1A1comprises 507 amino acids and has a predicted molecular mass of 41.5 kDa. It migrates as an approximately 45-50 kDa band in SDS-PAGE under reducing conditions.
50 µg/$441
ALDH1A1 / ALDH1 Protein - Purified recombinant protein ALDH1A1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
54.7 kDa
20 µg/$1,107
ALDH1A1 / ALDH1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Select
E. coli
6His, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
57kD
10 µg/$281; 50 µg/$420; 500 µg/$1,585; 1 mg/$2,157
ALDH1A1 / ALDH1 Protein - Recombinant Aldehyde Dehydrogenase 1 Family, Member A1 By SDS-PAGE
Select
E. coli
His-T7
58.4 kDa
10 µg/$267; 50 µg/$357; 100 µg/$572; 200 µg/$712; 1 mg/$1,741; 500 µg/$1,313; 5 mg/$2,695; 2 mg/$1,920
ALDH1A1 / ALDH1 Protein - 12.5% SDS-PAGE of human ALDH1A1 stained with Coomassie Blue
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Wheat Germ Extract
GST
80.63 kDa
10 µg/$479; 25 µg/$670
ALDH1A1 / ALDH1 Protein - 12.5% SDS-PAGE of human ALDH1A1 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
81.3 kDa
10 µg/$479; 25 µg/$670
Select
E. coli
6His, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
57.0 kDa
10 µg/$368; 50 µg/$504
ALDH1A1 / ALDH1 Protein - Recombinant Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) by SDS-PAGE
Select
E. coli
His-T7, N-terminus
39.0kDa
10 µg/$272; 50 µg/$387; 200 µg/$772; 100 µg/$620; 1 mg/$1,834; 500 µg/$1,393; 5 mg/$2,794; 2 mg/$2,016
ALDH1A1 / ALDH1 Protein - Active Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) by WB
Select
E. coli
His, N-Terminal
58kDa
10 µg/$345; 50 µg/$842; 200 µg/$1,480; 1 mg/$2,788; 5 mg/$5,881; 2 mg/$3,137
ALDH1A1 / ALDH1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
54.7 kDa
100 µg/$494
Select
293T Cells
Myc-DDK (Flag)
54.7 kDa
20 µg/$150
Viewing 1-14 of 14 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).