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ALDH1A1 / ALDH1
aldehyde dehydrogenase 1 family, member A1
ALDH1A1 / ALDH1 belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet.
| Gene Name: | aldehyde dehydrogenase 1 family, member A1 |
| Synonyms: | ALDH1A1, Acetaldehyde dehydrogenase 1, ALDH class 1, ALDC, Aldehyde dehydrogenase 1, ALDH-E1, ALDH1, ALDH11, PUMB1, RALDH 1, RALDH1, ALHDII, Retinal dehydrogenase 1, Retinaldehyde dehydrogenase 1 |
| Target Sequences: | NM_000689 NP_000680.2 P00352 |
Publications (3)
1
Targeting Breast Cancer Stem Cell State Equilibrium through Modulation of Redox Signaling. Ming Luo, Li Shang, Michael D Brooks, Evelyn Jiagge, Yongyou Zhu, Johanna M Buschhaus, Sarah Conley, Melissa A Fath, April Davis, Elizabeth Gheordunescu, Yongfang Wang, Ramdane Harouaka, Ann Lozier, Daniel Triner, Sean McDermott, Sofia D Merajver, Gary D Luker, Douglas R Spitz, Max S Wicha. Cell metabolism. 2018 July;28:69-86.e6. [Full Text Article]
[PubMed:29972798]
[PMC:PMC6037414]
2
BRCA1 mutation influences progesterone response in human benign mammary organoids. Batzaya Davaadelger, Mi-Ran Choi, Hari Singhal, Susan E Clare, Seema A Khan, J Julie Kim. Breast cancer research : BCR. 2019 Nov;21:124. [Full Text Article]
[PubMed:31771627]
[PMC:PMC6878650]
Related Antibodies: LS-B10149.
3
Expanding the use of monoclonal antibody therapy of cancer by using ionising radiation to upregulate antibody targets. Wattenberg MM, Kwilas AR, Gameiro SR, Dicker AP, Hodge JW. British journal of cancer. 2014 Mar;110:1472-80. [Full Text Article]
[PubMed:24556625]
[PMC:PMC3960628]
Related Antibodies: LS-B2497.
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(7)
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Cancer
ALDH1A1 / ALDH1 Mouse anti-Human Monoclonal Antibody
Human
IF, IHC-P, WB
Unconjugated
200 µl/$460
ALDH1A1 / ALDH1 Goat anti-Human Polyclonal (aa476-488) Antibody
Sheep, Bovine, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
Cancer
ALDH1A1 / ALDH1 Mouse anti-Human Monoclonal (1G6) Antibody
Human
ELISA, IHC-P, IP, WB
Unconjugated
50 µg/$460
ALDH1A1 / ALDH1 Rabbit anti-Human Polyclonal Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
ALDH1A1 / ALDH1 Rabbit anti-Human Polyclonal (aa302-331) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
ALDH1A1 / ALDH1 Rabbit anti-Human Polyclonal (aa202-501) Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
Cancer
ALDH1A1 / ALDH1 Mouse anti-Human Monoclonal (5A11) Antibody
Human
ELISA, IHC-P, WB
Unconjugated
50 µl/$440
E. coli
None
100 µg/$342; 500 µg/$641; 20 µg/$254
ALDH1A1 / ALDH1 Rabbit anti-Human Polyclonal (aa302-331) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
200 µl/$734
ALDH1A1 / ALDH1 Rabbit anti-Human Polyclonal (aa302-331) (Biotin) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
Biotin Conjugated
200 µl/$952
ALDH1A1 / ALDH1 Rabbit anti-Human Polyclonal (aa302-331) (FITC) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
FITC Conjugated
200 µl/$952
ALDH1A1 / ALDH1 Rabbit anti-Human Polyclonal (aa302-331) (APC) Antibody
Human
FLISA, ICC, IF, IHC-P, WB
APC Conjugated
200 µl/$952
ALDH1A1 / ALDH1 Rabbit anti-Human Polyclonal (aa302-331) (PE) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
PE Conjugated
200 µl/$952
ALDH1A1 / ALDH1 Rabbit anti-Human Polyclonal (aa302-331) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
ALDH1A1 / ALDH1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Yeast
6His, N-terminus
1 mg/$1,973; 100 µg/$570; 20 µg/$395
Cancer
ALDH1A1 / ALDH1 Rabbit anti-Human Polyclonal Antibody
Human
IHC-P, WB
Unconjugated
100 µl/$485
ALDH1A1 / ALDH1 Goat anti-Human Polyclonal (aa488-501) Antibody
Rabbit, Horse, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
ALDH1A1 / ALDH1 Mouse anti-Human Monoclonal (2B2G1) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µl/$459
ALDH1A1 / ALDH1 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
ALDH1A1 / ALDH1 Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, ICC, IF, WB
Unconjugated
20 µl/$271; 100 µl/$412
ALDH1A1 / ALDH1 Rabbit anti-Human Monoclonal (EP168) Antibody
Human
IHC-Fr, IHC-P
Unconjugated
0.1 ml/$321; 0.5 ml/$512; 1 ml/$840
ALDH1A1 / ALDH1 Rabbit anti-Human Monoclonal (Ready-to-Use) (EP168) Antibody
Human
IHC-Fr, IHC-P
Unconjugated, Ready-to-Use
3 ml/$311; 7 ml/$512; 15 ml/$899
ALDH1A1 / ALDH1 Mouse anti-Human Monoclonal (FITC) Antibody
Human
Flo
FITC Conjugated
25 Tests/$278; 100 Tests/$346
ALDH1A1 / ALDH1 Mouse anti-Human Monoclonal (Biotin) (152CT1.2.2) Antibody
Human
ELISA, ICC, IF, IHC, WB
Biotin Conjugated
200 µl/$952
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