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ALDH18A1

aldehyde dehydrogenase 18 family, member A1

ALDH18A1 is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene.

Gene Name: aldehyde dehydrogenase 18 family, member A1
Synonyms: ALDH18A1, p5CS, PYCS, ARCL3A, GSAS
Target Sequences: NM_002860 NP_002851.2 P54886

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Products
Antibodies (21)
Primary (21)
ALDH18A1 (21)
Human (21)
Mouse (8)
Rat (5)
Bovine (4)
Chimpanzee (3)
Dog (1)
Gibbon (3)
Guinea pig (3)
Hamster (1)
Horse (4)
Monkey (1)
Orangutan (3)
Pig (4)
IHC (2)
IHC-P (1)
WB (20)
Flo (1)
ELISA (9)
IP (3)
Peptide-ELISA (2)
rabbit (19)
mouse (1)
goat (1)
IgG (12)
IgG2b,k (1)
monoclonal mc (1)
polyclonal pc (20)
2B5 (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (13)
aa176-205 (7)
aa35-84 (4)
aa10-257 (1)
aa575-625 (1)
aa745-795 (1)
aa775-784 (1)
No (21)
ALDH18A1 Antibody - ALDH18A1 antibody (1 ug/ml) staining of MCF7 lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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ALDH18A1 Goat anti-Human Polyclonal (aa775-784) Antibody
Mouse, Dog, Bovine, Hamster, Pig, Horse, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
ALDH18A1 Antibody
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ALDH18A1 Rabbit anti-Human Polyclonal (aa10-257) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$332
ALDH18A1 Antibody - Formalin-fixed and paraffin-embedded human brain tissue reacted with ALDH18A1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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ALDH18A1 Rabbit anti-Human Polyclonal (aa176-205) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
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ALDH18A1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$331
ALDH18A1 Antibody - ALDH18A1 monoclonal antibody (M01), clone 2B5 Western Blot analysis of ALDH18A1 expression in MCF-7.
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ALDH18A1 Mouse anti-Human Monoclonal (2B5) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
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ALDH18A1 Rabbit anti-Human Polyclonal (aa176-205) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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ALDH18A1 Rabbit anti-Human Polyclonal (aa176-205) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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ALDH18A1 Rabbit anti-Human Polyclonal (aa176-205) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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ALDH18A1 Rabbit anti-Human Polyclonal (aa176-205) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
ALDH18A1 Rabbit anti-Human Polyclonal (aa176-205) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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ALDH18A1 Rabbit anti-Human Polyclonal (aa176-205) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
ALDH18A1 Antibody - Detection of human and mouse ALDH18A1/P5CS by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, Jurkat, mouse TCMK-1, and mouse NIH 3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-ALDH18A1/P5CS antibody used for WB at 0.04 µg/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.
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ALDH18A1 Rabbit anti-Human Polyclonal (aa575-625) Antibody
Mouse, Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
ALDH18A1 Antibody - Western blot analysis of extracts of HepG2 cells using P5CS antibody. The lane on the left was treated with blocking peptide.
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ALDH18A1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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ALDH18A1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
ALDH18A1 Antibody - ALDH18A1 / P5CS antibody Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ALDH18A1 Rabbit anti-Human Polyclonal (aa35-84) Antibody
Human
WB
Unconjugated
100 µl/$424
ALDH18A1 Antibody - ALDH18A1 / P5CS antibody Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ALDH18A1 Rabbit anti-Human Polyclonal (aa35-84) (HRP) Antibody
Mouse, Guinea pig, Bovine, Pig, Horse, Rat, Chimpanzee, Orangutan, Gibbon, Human
WB
HRP Conjugated
100 µl/$469
ALDH18A1 Antibody - ALDH18A1 / P5CS antibody Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ALDH18A1 Rabbit anti-Human Polyclonal (aa35-84) (Biotin) Antibody
Mouse, Guinea pig, Bovine, Pig, Horse, Rat, Chimpanzee, Orangutan, Gibbon, Human
WB
Biotin Conjugated
100 µl/$469
ALDH18A1 Antibody - ALDH18A1 / P5CS antibody Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ALDH18A1 Rabbit anti-Human Polyclonal (aa35-84) (FITC) Antibody
Mouse, Guinea pig, Bovine, Pig, Horse, Rat, Chimpanzee, Orangutan, Gibbon, Human
WB
FITC Conjugated
100 µl/$469
ALDH18A1 Antibody - Western blot analysis of extracts of various cell lines, using ALDH18A1 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
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ALDH18A1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
ALDH18A1 Antibody - Western blot analysis of P5CS expression in HCT116 (A), Panc1 (B), SGC7901 (C), A375 (D), mouse embryo (E) whole cell lysates.
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ALDH18A1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
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ALDH18A1 Rabbit anti-Human Polyclonal (aa745-795) Antibody
Human
IP
Unconjugated
10 µl/$295; 100 µl/$514
Viewing 1-21 of 21 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).