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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ALAS1

aminolevulinate, delta-, synthase 1

ALAS1 encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene Name: aminolevulinate, delta-, synthase 1
Synonyms: ALAS1, ALAS, ALAS-H, ALAS3, ALASH, Delta-ALA synthase 1, MIG4, Migration-inducing protein 4
Target Sequences: NM_000688 NP_000679.1 P13196

Filtered By: None
Target
ALAS1 (22)
Reactivity
Human (21)
Mouse (8)
Rat (8)
Bovine (4)
Chimpanzee (6)
Dog (4)
Gibbon (3)
Guinea pig (4)
Horse (4)
Monkey (4)
Zebrafish (3)
Application
IHC (8)
IHC-P (6)
WB (15)
ELISA (3)
ICC (1)
IF (4)
Host
rabbit (20)
mouse (2)
Isotype
IgG (14)
IgG1 (1)
IgG2a,k (1)
Clonality
monoclonal mc (3)
polyclonal pc (19)
Clone
1C5 (1)
3G10 (1)
Format
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
Unconjugated (13)
Epitope
aa146-195 (4)
aa46-95 (4)
aa1-250 (1)
aa480-530 (1)
aa57-308 (1)
Publications
No (21)
Yes (1)
Showing 1-22 of 22 results

ALAS1 Antibody (aa480-530) IHC-plus™ LS-B2013
Publications (1)
Publications (1)
Rabbit Polyclonal (IgG) to Human ALAS1
Human
IHC IHC-P WB
Unconjugated
50µg 0.5mg/ml  $425.00
Anti-ALAS1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Western blot of ALAS-1 in HepG2 cell lysate using antibody at 1 ug/ml.
Anti-ALAS1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Western blot of ALAS-1 in HepG2 cell lysate using antibody at 1 ug/ml.

ALAS1 Antibody LS-C497774
Rabbit Monoclonal to Human ALAS1
Human
IF WB
Unconjugated
50µl  $295.00; 100µl  $385.00; 200µl  $560.00
Immunofluorescence analysis of MCF-7 cells using ALAS1 antibody.
Immunofluorescence analysis of HeLa cells using ALAS1 antibody.
Immunofluorescence analysis of MCF-7 cells using ALAS1 antibody.
Immunofluorescence analysis of HeLa cells using ALAS1 antibody.

ALAS1 Antibody (aa146-195) IHC-plus™ LS-B12725
Rabbit Polyclonal (IgG) to Human ALAS1
Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Human, Monkey
IHC IHC-P WB
Unconjugated
50µg  $485.00
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Fetal lung lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Fetal lung lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

ALAS1 Antibody (aa146-195, HRP) LS-C458429
Rabbit Polyclonal (IgG) to Human ALAS1
Zebrafish, Horse, Mouse, Dog, Guinea pig, Bovine, Rat, Human, Monkey, Gibbon, Chimpanzee
IHC IHC-P WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Fetal lung lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Fetal lung lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

ALAS1 Antibody (aa146-195, Biotin) LS-C458427
Rabbit Polyclonal (IgG) to Human ALAS1
Zebrafish, Horse, Mouse, Dog, Guinea pig, Bovine, Rat, Human, Monkey, Gibbon, Chimpanzee
IHC IHC-P WB
Biotin Conjugated
100µl 1mg/ml  $385.00
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Fetal lung lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Fetal lung lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

ALAS1 Antibody (aa146-195, FITC) LS-C458428
Rabbit Polyclonal (IgG) to Human ALAS1
Zebrafish, Horse, Mouse, Dog, Guinea pig, Bovine, Rat, Human, Monkey, Gibbon, Chimpanzee
IHC IHC-P WB
FITC Conjugated
100µl 1mg/ml  $385.00
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Fetal lung lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Fetal lung lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

ALAS1 Antibody (aa1-250) LS-C334773
Rabbit Polyclonal (IgG) to Human ALAS1
Mouse, Rat, Human
IF IHC WB
Unconjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Immunofluorescence analysis of HeLa cells.
Western blot analysis of extracts of various cell lines.
Immunofluorescence analysis of HeLa cells.
Western blot analysis of extracts of various cell lines.

ALAS1 Antibody LS-C482631
Rabbit Polyclonal to Human ALAS1
Human
ICC IF WB
Unconjugated
50µl 1mg/ml  $255.00; 100µl 1mg/ml  $295.00; 200µl 1mg/ml  $375.00
Immunofluorescent analysis of ALAS-H staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
Western blot analysis of ALAS-H expression in SW620 (A); HepG2 (B); mouse liver (C) whole cell lysates.
Immunofluorescent analysis of ALAS-H staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
Western blot analysis of ALAS-H expression in SW620 (A); HepG2 (B); mouse liver (C) whole cell lysates.

ALAS1 Antibody LS-C748510
Rabbit Polyclonal (IgG) to Human ALAS1
Mouse, Rat, Human
IF WB
Unconjugated
50µl  $235.00

ALAS1 Antibody LS-C404478
Rabbit Polyclonal (IgG) to Human ALAS1
Mouse, Rat, Human
ELISA IHC
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human breast cancer using ALAS1 Polyclonal Antibody at dilution of 1:15.
Immunohistochemistry of Human breast cancer using ALAS1 Polyclonal Antibody at dilution of 1:15.

ALAS1 Antibody LS-C401209
Rabbit Polyclonal (IgG) to Human ALAS1
Mouse, Rat, Human
ELISA IHC
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human thyroid cancer using ALAS1 Polyclonal Antibody at dilution of 1:30.
Immunohistochemistry of Human thyroid cancer using ALAS1 Polyclonal Antibody at dilution of 1:30.
Immunohistochemistry of Human thyroid cancer using ALAS1 Polyclonal Antibody at dilution of 1:30.
Immunohistochemistry of Human thyroid cancer using ALAS1 Polyclonal Antibody at dilution of 1:30.

ALAS1 Antibody (clone 3G10) LS-C196635
Mouse Monoclonal [clone 3G10] (IgG2a,k) to Human ALAS1
Human
ELISA WB
Unconjugated
100µg  $355.00
ALAS1 monoclonal antibody (M01), clone 3G10 Western Blot analysis of ALAS1 expression in JAR.
Detection limit for recombinant GST tagged ALAS1 is approximately 0.1 ng/ml as a capture antibody.
ALAS1 monoclonal antibody (M01), clone 3G10 Western Blot analysis of ALAS1 expression in JAR.
Detection limit for recombinant GST tagged ALAS1 is approximately 0.1 ng/ml as a capture antibody.

ALAS1 Antibody (aa57-308, clone 1C5) LS-C340448
Mouse Monoclonal [clone 1C5] (IgG1) to Human ALAS1
Human
WB
Unconjugated
100µl 1mg/ml  $335.00
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ALAS1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ALAS1 (1:2000).
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ALAS1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ALAS1 (1:2000).

ALAS1 Antibody (aa46-95) LS-C206108
Rabbit Polyclonal to Human ALAS1
Human
WB
Unconjugated
50µg  $365.00
ALAS1 antibody Western Blot of 293T. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
ALAS1 antibody Western Blot of 293T. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

ALAS1 Antibody (aa46-95, HRP) LS-C479348
Rabbit Polyclonal to Human ALAS1
Human, Chimpanzee
WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
ALAS1 antibody Western Blot of 293T. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
ALAS1 antibody Western Blot of 293T. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

ALAS1 Antibody (aa46-95, Biotin) LS-C479346
Rabbit Polyclonal to Human ALAS1
Human, Chimpanzee
WB
Biotin Conjugated
100µl 1mg/ml  $385.00
ALAS1 antibody Western Blot of 293T. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
ALAS1 antibody Western Blot of 293T. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

ALAS1 Antibody (aa46-95, FITC) LS-C479347
Rabbit Polyclonal to Human ALAS1
Human, Chimpanzee
WB
FITC Conjugated
100µl 1mg/ml  $385.00
ALAS1 antibody Western Blot of 293T. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
ALAS1 antibody Western Blot of 293T. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

ALAS1 Antibody LS-C675116
Rabbit Polyclonal (IgG) to Human ALAS1
Human
IHC-P
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry image of paraffin-embedded human liver cancer at a dilution of 1:100
Immunohistochemistry image of paraffin-embedded human lung cancer at a dilution of 1:100
Immunohistochemistry image of paraffin-embedded human liver cancer at a dilution of 1:100
Immunohistochemistry image of paraffin-embedded human lung cancer at a dilution of 1:100

ALAS1 Antibody (HRP) LS-C673269
Rabbit Polyclonal (IgG) to Human ALAS1
Human
HRP Conjugated
50µg  $285.00; 100µg  $385.00

ALAS1 Antibody (Biotin) LS-C673272
Rabbit Polyclonal (IgG) to Human ALAS1
Human
Biotin Conjugated
50µg  $285.00; 100µg 0.25mg/ml  $385.00

ALAS1 Antibody (FITC) LS-C673271
Rabbit Polyclonal (IgG) to Human ALAS1
Human
FITC Conjugated
50µg  $285.00; 100µg  $385.00

ALAS1 Antibody LS-C185224
Rabbit Polyclonal (IgG)
Unconjugated
100µg  $920.00
Showing 1-22 of 22 results

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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