AKR7A2 / AFAR

aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)

Catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate. May have an important role in producing the neuromodulator gamma-hydroxybutyrate (GHB). Has broad substrate specificity. Has NADPH-dependent aldehyde reductase activity towards 2-carboxybenzaldehyde, 2-nitrobenzaldehyde and pyridine-2-aldehyde (in vitro). Can reduce 1,2-naphthoquinone and 9,10-phenanthrenequinone (in vitro). Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.

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Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

AKR7A2 / AFAR (5)

Publications

No (5)

Tag

GST (2)

His (1)

Myc-DDK (Flag) (2)

Species

Human (4)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (3)

Biologically Active

Biologically active (1)

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AKR7A2 / AFAR Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117152

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39.4 kDa

Price:

100 µg/$494

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Human AKR7A2 / AFAR Protein (Recombinant GST) (Full Length) - LS-G31220

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

61.82 kDa

Price:

10 µg/$479; 25 µg/$670

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Human AKR7A2 / AFAR Protein (Recombinant GST) (Full Length) - LS-G31222

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

61.82 kDa

Price:

10 µg/$479; 25 µg/$670

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Human AKR7A2 / AFAR Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80374

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39.4 kDa

Price:

20 µg/$150

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Human AKR7A2 / AFAR Protein (Recombinant His) - LS-G698

Source:

E. coli

Tag:

His

Biological Activity:

Biologically active

Price:

100 µg/$411; 500 µg/$985; 20 µg/$276

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