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Required for the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6. Forms a complex with YWHAB that acts to repress transcription of DUSP1.
Gene Name: | akirin 2 |
Synonyms: | AKIRIN2, Akirin 2, C6orf166, DJ486L4.2, Akirin-2, FBI1 |
Target Sequences: | NM_018064 NP_060534.1 Q53H80 |
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