AK1 / Adenylate Kinase 1

adenylate kinase 1

Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. AK1 is involved in the adenine nucleotide catabolic pathway, production of ADP, and in the homeostasis of guanine nucleotide pools. Adenylate kinase 1 phosphorylates AMP in red blood cells; deficiency in AK1 is the cause nonspherocytic hemolytic anemia. This small ubiquitous enzyme is essential for maintenance and cell growth. Three isozymes of adenylate kinase have been identified in vertebrates. AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. Alternative splicing of the AK1 gene yields two transcripts that differ in the 3-prime non-coding region and use two distinct polyadenylation signals.

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Products

Proteins (7)

Type

Over-Expression Lysate (2)

Recombinant (5)

Target

AK1 / Adenylate Kinase 1 (7)

Publications

No (7)

Tag

GST (1)

His (1)

His,N-terminus (1)

His-SUMO (1)

Myc-DDK (Flag) (3)

Species

Human (6)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (2)

Biologically Active

Biologically active (1)

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Human AK1 / Adenylate Kinase 1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G64839

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

21.5 kDa

Price:

20 µg/$1,107

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Human AK1 / Adenylate Kinase 1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74330

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

21.5 kDa

Price:

20 µg/$150

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Human AK1 / Adenylate Kinase 1 Protein (Recombinant His-SUMO) (Full Length) - LS-G20468

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

37.61 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human AK1 / Adenylate Kinase 1 Protein (Recombinant GST) (Full Length) - LS-G27405

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

47.08 kDa

Price:

10 µg/$479; 25 µg/$670

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Human AK1 / Adenylate Kinase 1 Protein (Recombinant His,N-terminus) (Met1-Lys194) - LS-G137930

Source:

E. coli

Tag:

His,N-terminus

Molecular Weight:

23.5 kDa

Price:

50 µg/$561

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Human AK1 / Adenylate Kinase 1 Protein (Recombinant His) - LS-G995

Source:

E. coli

Tag:

His

Biological Activity:

Biologically active

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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AK1 / Adenylate Kinase 1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99056

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

21.5 kDa

Price:

100 µg/$494

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