AIM2

absent in melanoma 2

Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent, caspase-1-independent cell death that involves caspase-8 (By similarity). Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity.

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Products

Antibodies (57)

Type

Primary (57)

Target

AIM2 (57)

Reactivity

Human (56)

Mouse (6)

Rat (1)

Gibbon (3)

Horse (3)

Monkey (3)

Pig (8)

Rabbit (5)

Zebrafish (3)

Application

IHC (11)

IHC-P (4)

WB (48)

Flo (8)

ELISA (20)

ICC (7)

IF (14)

IP (1)

Peptide-ELISA (6)

Host

rabbit (48)

mouse (6)

goat (3)

Product Group

IHCPlus (1)

Isotype

IgG (34)

IgG1 (2)

IgG2a,k (2)

IgM (1)

Clonality

monoclonal mc (5)

polyclonal pc (52)

Clone

3C4G11 (1)

7G12D1 (1)

812CT9.2.2.1 (1)

IMG10M2B3 (1)

IMG10M5G5 (1)

Format

APC (1)

APC Conjugated (3)

Azide-free (1)

Biotin Conjugated (5)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (5)

HRP Conjugated (5)

PE Conjugated (3)

Unconjugated (34)

Epitope

aa1-343 (8)

aa4-32 (7)

N-Terminus (4)

Internal (2)

30-110 aa, Internal (1)

Ala78 (1)

C-Terminus (1)

Internal Region (1)

Internal region (near N-Terminus) (1)

aa14-215 (1)

aa29-78 (1)

aa51-100 (1)

aa93-342 (1)

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Publications

No (57)

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AIM2 Antibody (aa4-32) LS-C156196

Antibody:

AIM2 Rabbit anti-Human Polyclonal (aa4-32) Antibody

Reactivity:

Human

Applications:

Flo, IF, WB

Format:

Unconjugated

Price:

400 µl/$393

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AIM2 Antibody (aa14-215) LS-C407895

Antibody:

AIM2 Rabbit anti-Human Polyclonal (aa14-215) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

AIM2 Antibody (N-Terminus) LS-C81558

Antibody:

AIM2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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AIM2 Antibody LS-C137251

Antibody:

AIM2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$332

Select

IHC-plus™ AIM2 Antibody (C-Terminus) LS-B5945

(4.0) Rating

Antibody:

AIM2 Goat anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µg/$485

Select

AIM2 Antibody LS-C804624

Antibody:

AIM2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

AIM2 Antibody (aa93-342) LS-C178548

Antibody:

AIM2 Rabbit anti-Human Polyclonal (aa93-342) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$332

Select

AIM2 Antibody LS-C498354

Antibody:

AIM2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

AIM2 Antibody (aa4-32) LS-C319389

Antibody:

AIM2 Rabbit anti-Human Polyclonal (aa4-32) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

AIM2 Antibody (aa4-32, Biotin) LS-C251075

Antibody:

AIM2 Rabbit anti-Human Polyclonal (aa4-32) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, IF, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

AIM2 Antibody (aa4-32, FITC) LS-C251076

Antibody:

AIM2 Rabbit anti-Human Polyclonal (aa4-32) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, IF, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

AIM2 Antibody (aa4-32, APC) LS-C251074

Antibody:

AIM2 Rabbit anti-Human Polyclonal (aa4-32) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, IF, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

AIM2 Antibody (aa4-32, Azide-free, HRP) LS-C251077

Antibody:

AIM2 Rabbit anti-Human Polyclonal (aa4-32) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, IF, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

AIM2 Antibody (aa4-32, PE) LS-C251078

Antibody:

AIM2 Rabbit anti-Human Polyclonal (aa4-32) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, IF, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

AIM2 Antibody (30-110 aa, Internal) LS-C381956

Antibody:

AIM2 Rabbit anti-Human Polyclonal (30-110 aa, Internal) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

AIM2 Antibody (clone 7G12D1) LS-C669398

Antibody:

AIM2 Mouse anti-Human Monoclonal (7G12D1) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µl/$459

Select

AIM2 Antibody LS-C659200

Antibody:

AIM2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

AIM2 Antibody (Internal) LS-C137125

Antibody:

AIM2 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µl/$332

Select

AIM2 Antibody LS-C815848

Antibody:

AIM2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC-P

Format:

Unconjugated

Price:

100 µl/$412

Select

AIM2 Antibody (clone 3C4G11) LS-C669272

Antibody:

AIM2 Mouse anti-Human Monoclonal (3C4G11) Antibody

Reactivity:

Human

Applications:

ELISA, Flo

Format:

Unconjugated

Price:

100 µl/$459

Select

AIM2 Antibody (Ala78) LS-C192022

Antibody:

AIM2 Rabbit anti-Human Polyclonal (Ala78) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

Select

AIM2 Antibody LS-C401421

Antibody:

AIM2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

AIM2 Antibody LS-C306161

Antibody:

AIM2 Mouse anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, WB

Format:

Unconjugated

Price:

50 µg/$705

Select

AIM2 Antibody LS-C823378

Antibody:

AIM2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

AIM2 Antibody LS-C309372

Antibody:

AIM2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µl/$749

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