Products
Services
Research Areas
Resources
Contact Us
Distributors
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Services
Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
Contact Us
LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121
Phone:
866-819-4732 (Toll Free North America
206-374-1102 (International)
Fax:
866-206-6909 (Toll Free North America)
206-577-4565 (International)
How To Buy - Details about how to buy our products.
Orders@LSBio.com - To submit a new order.
Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, froforma invoice requests, or other billing issues.
Technical.Support@LSBio.com - To request technical information about an LSBio product or its applications
Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.
Worldwide Distributors List - To find your local distributor if you're not within the United States.
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

AIM2

absent in melanoma 2

Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent, caspase-1-independent cell death that involves caspase-8 (By similarity). Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity.

Gene Name: absent in melanoma 2
Synonyms: AIM2, Absent in melanoma 2, PYHIN4
Target Sequences: NM_004833 NP_004824.1 O14862

Viewing 1-25 of 58 items
AIM2 Antibody - Anti-AIM2 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Select
Goat Polyclonal to Human AIM2
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µg   0.5mg/ml   $425.00
AIM2 Antibody - Immunohistochemical analysis of AIM2 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
Rabbit Polyclonal to Human AIM2
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100µl   1mg/ml   $245.00
AIM2 Antibody - Confocal immunofluorescence of AIM2 Antibody with MCF-7 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red). DAPI was used to stain the cell nuclear (blue).
Select
Rabbit Polyclonal to Human AIM2
Human
Flo, IF, WB
Unconjugated
400µl   $325.00
AIM2 Antibody - Fetal lung lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human AIM2
Zebrafish, Horse, Mouse, Human, Monkey
WB
Unconjugated
100µl   0.5mg/ml   $365.00
AIM2 Antibody - AIM2 antibody IHC-paraffin. IHC(P): Mouse Kidney Tissue.
Select
Rabbit Polyclonal to Human AIM2
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100µg   $355.00
AIM2 Antibody
Select
Rabbit Polyclonal (IgG) to Human AIM2
Human
IHC, WB
Unconjugated
100µl   1mg/ml   $265.00
Select
Rabbit Polyclonal (IgG) to Human AIM2
Human
ELISA, Flo, IF, WB
Unconjugated
200µl   $590.00
Select
Rabbit Polyclonal (IgG) to Human AIM2
Human
ELISA, Flo, ICC, IF, WB
Biotin Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human AIM2
Human
ELISA, Flo, ICC, IF, WB
FITC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human AIM2
Human
ELISA, Flo, ICC, IF, WB
APC Conjugated
200µl   0.35mg/ml   $740.00
Select
Rabbit Polyclonal (IgG) to Human AIM2
Human
ELISA, Flo, ICC, IF, WB
PE Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human AIM2
Human
ELISA, Flo, ICC, IF, WB
AP Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human AIM2
Human
ELISA, Flo, ICC, IF, WB
HRP Conjugated, Azide-free
200µl   $740.00
AIM2 Antibody
Select
Rabbit Polyclonal to Human AIM2
Human
ELISA, IHC, WB
Unconjugated
100µg   1mg/ml   $265.00
AIM2 Antibody - Immunohistochemistry of paraffin-embedded human testis tissue using AIM2 Antibody at dilution of 1:100
Select
Rabbit Polyclonal (IgG) to Human AIM2
Human
ELISA, IF, IHC, WB
Unconjugated
50µg   $285.00; 100µg   $385.00
AIM2 Antibody - Western blot of AIM2 antibody
Select
Rabbit Polyclonal (IgG) to Human AIM2
Human
ELISA, IF, IHC, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
AIM2 Antibody - Staining HuvEc cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
Select
Rabbit Polyclonal (IgG) to Human AIM2
Mouse, Human
ELISA, IF, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
Select
Mouse Monoclonal [clone 7G12D1] (IgG1) to Human AIM2
Human
ELISA, IF, WB
Unconjugated
100µl   $365.00
Select
Rabbit Polyclonal (IgG) to Human AIM2
Human
ELISA, IHC, WB
Unconjugated
100µg   $405.00
AIM2 Antibody
Select
Rabbit Polyclonal (IgG) to Human AIM2
Human
ELISA, IHC, WB
Unconjugated
100µl   1mg/ml   $265.00
AIM2 Antibody - Immunochemical staining of human AIM2 in human liver with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
Select
Rabbit Polyclonal (IgG) to Human AIM2
Human
ICC, IF, IHC-P
Unconjugated
50µl   $235.00; 100µl   $275.00; 200µl   $305.00
Select
Mouse Monoclonal [clone 3C4G11] (IgG1) to Human AIM2
Human
ELISA, Flo
Unconjugated
100µl   $365.00
Select
Rabbit Polyclonal to Human AIM2
Human
IHC, WB
Unconjugated
100µl   $345.00
AIM2 Antibody - Immunohistochemistry of paraffin-embedded Human lung cancer using AIM2 Polyclonal Antibody at dilution of 1:60.
Select
Rabbit Polyclonal (IgG) to Human AIM2
Human
ELISA, IHC
Unconjugated
20µl   0.8mg/ml   $205.00; 60µl   0.8mg/ml   $235.00; 120µl   0.8mg/ml   $295.00; 200µl   0.8mg/ml   $395.00
Select
Mouse Polyclonal (IgG) to Human AIM2
Human
IF, WB
Unconjugated
50µg   $560.00

Viewing 1-25 of 58 items


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).