Products
Research Areas
COVID-19
Resources
Contact Us
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Cart
How To Buy
Contact Us

Locations

Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464

Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers


Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us


Additional Contact Details

Distributors
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

AHR

aryl hydrocarbon receptor

Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1.

Gene Name: aryl hydrocarbon receptor
Synonyms: AHR, Ah receptor, AH-receptor, Aryl hydrocarbon receptor, BHLHe76, Aromatic hydrocarbon receptor
Target Sequences: NM_001621 NP_001612.1 P35869

Publications (9)

1
Characterization of polyclonal antibodies to the Ah receptor prepared by immunization with a synthetic peptide hapten. Poland A, Glover E, Bradfield CA. Molecular pharmacology. 1991 39:20-6. [PubMed:1846218]
2
Baculovirus expression of the Ah receptor and Ah receptor nuclear translocater. Evidence for additional dioxin responsive element-binding species and factors required for signaling. Chan WK, Chu R, Jain S, Reddy JK, Bradfield CA. The Journal of biological chemistry. 1994 269:26464-71. [PubMed:7929368]
3
Possible involvement of aryl hydrocarbon receptor (AhR) in adult T-cell leukemia (ATL) leukemogenesis: constitutive activation of AhR in ATL. Hayashibara T, Yamada Y, Mori N, Harasawa H, Sugahara K, Miyanishi T, Kamihira S, Tomonaga M. Biochemical and biophysical research communications. 2003 300:128-34. [PubMed:12480531]
4
Mutational analysis of the mouse aryl hydrocarbon receptor tyrosine residues necessary for recognition of dioxin response elements. Minsavage GD, Vorojeikina DP, Gasiewicz TA. Archives of biochemistry and biophysics. 2003 412:95-105. [PubMed:12646272]
5
Critical enhancer region to which AhR/ARNT and Sp1 bind in the human CYP1B1 gene. Tsuchiya Y, Nakajima M, Yokoi T. Journal of biochemistry. 2003 133:583-92. [PubMed:12801909]
6
Combined screening of thymocytes using apoptosis-specific cDNA array and promoter analysis yields novel gene targets mediating TCDD-induced toxicity. Fisher MT, Nagarkatti M, Nagarkatti PS. Toxicological sciences : an official journal of the Society of Toxicology. 2004 78:116-24. [PubMed:14718646]
7
Aryl hydrocarbon receptor is activated by glucose and regulates the thrombospondin-1 gene promoter in endothelial cells. Dabir P, Marinic TE, Krukovets I, Stenina OI. Circulation research. 2008 102:1558-65. [PubMed:18515748] [PMC:PMC2740473]
8
Interaction of aryl hydrocarbon receptor and NF-B subunit RelB in breast cancer is associated with interleukin-8 overexpression. Vogel CF, Li W, Wu D, Miller JK, Sweeney C, Lazennec G, Fujisawa Y, Matsumura F. Archives of biochemistry and biophysics. 2011 512:78-86. (IHC; Human) [PubMed:21640702] [PMC:PMC3135412]
9
Functional expression of aryl hydrocarbon receptor on mast cells populating human endometriotic tissues. Mariuzzi L, Domenis R, Orsaria M, Marzinotto S, Londero AP, Bulfoni M, Candotti V, Zanello A, Ballico M, Mimmi MC, Calcagno A, Marchesoni D, Di Loreto C, Beltrami AP, Cesselli D, Gri G. Laboratory investigation; a journal of technical methods and pathology. 2016 96:959-971. (IF; Human) [PubMed:27348627] [PMC:PMC5008463] Related Antibodies: LS-A3391.
more

☰ Filters
Products
Proteins (7)
Over-Expression Lysate (2)
Recombinant (5)
AHR (7)
No (7)
GST, N-terminus (2)
His (1)
His, N-Terminal (1)
His-GST (1)
Myc-DDK (Flag) (2)
Human (4)
Mouse (1)
Rat (1)
293T Cells (1)
E. coli (3)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (1)
AHR Protein - 12.5% SDS-PAGE of human AHR stained with Coomassie Blue
Select
Human AHR Protein (Recombinant GST, N-terminus) (Full Length) - LS-G27400
Wheat Germ Extract
GST, N-terminus
122.5 kDa
2 µg/$439
AHR Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
Human AHR Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74380
293T Cells
Myc-DDK (Flag)
96 kDa
20 µg/$150
AHR Protein
Select
Human AHR Protein (Recombinant His, N-Terminal) (aa128-399) - LS-G13702
E. coli
His, N-Terminal
32.5 kDa
10 µg/$313; 50 µg/$642; 100 µg/$1,020; 200 µg/$1,214; 1 mg/$2,450; 500 µg/$1,952; 5 mg/$4,481; 2 mg/$2,642
AHR Protein - Recombinant Aryl Hydrocarbon Receptor By SDS-PAGE
Select
Mouse AHR Protein (Recombinant His-GST) (aa126-385) - LS-G24287
E. coli
His-GST
59.5 kDa
10 µg/$289; 50 µg/$492; 100 µg/$785; 200 µg/$982; 1 mg/$2,119; 500 µg/$1,646; 5 mg/$3,431; 2 mg/$2,309
AHR Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
AHR Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118493
HEK 293 Cells
Myc-DDK (Flag)
96 kDa
100 µg/$494
AHR Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Human AHR Protein (Recombinant GST, N-terminus) (aa721-820) - LS-G57734
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
AHR Protein - Recombinant Aryl Hydrocarbon Receptor By SDS-PAGE
Select
Rat AHR Protein (Recombinant His) (aa311-579) - LS-G13703
E. coli
His
32.1 kDa
10 µg/$304; 50 µg/$587; 100 µg/$940; 200 µg/$1,133; 1 mg/$2,340; 500 µg/$1,848; 5 mg/$4,103; 2 mg/$2,532
Viewing 1-7 of 7 product results

(0) Selected Add Selected To Cart Compare Selected Clear Selected Top Of Search
Filtered By:
Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

Family of Companies
Site Links Home All Antibodies How To Buy All Proteins Distributors All ELISA & Assay Kits Reviews PathPlus™ Antibodies
Follow LSBio View Cart Register or Login
Copyright © 2022 LifeSpan BioSciences, Inc - Privacy Policy
Contact Us

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464

Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

To place an order:
Orders@LSBio.com

For questions about orders:
Customer.Support@LSBio.com

For technical assistance:
Technical.Support@LSBio.com