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AGTR2 / AT2 Receptor

angiotensin II receptor, type 2

Type 2 Angiotensin Receptor (AT2) has been suggested to affect development, cell differentiation, apoptosis, and regeneration in various tissues. AT2 receptor has been shown to exert counteracting effects on cellular growth and differentiation, vascular tone, and the release of arginine vasopressin (AVP). In each condition, the AT2 receptor appears to down-modulate actions mediated by the AT1 receptor, resulting in decreased cellular proliferation, decreased levels of serum AVP levels, or decreased vasoconstrictor responses. Binding of angiotensin II to the AT2 receptor inhibits guanylate cyclase. Recently, AT2 receptor has been suggested to affect brain development and cognitive function (Vervoort et al. 2002).

Gene Name: angiotensin II receptor, type 2
Family/Subfamily: GPCR , Angiotensin
Synonyms: AGTR2, Angiotensin ii receptor type 2, Angiotensin II type-2 receptor, AT2 receptor, AT2, At2r, MRX88, Angiotensin ii at2, Angiotensin receptor 2, Type-2 angiotensin II receptor, ATGR2
Target Sequences: NM_000686 NP_000677.2 P50052

Publications (2)

1
A Novel Swine Model of Spontaneous Hypertension With Sympathetic Hyperactivity Responds Well to Renal Denervation. Li D, Wang Q, Zhang Y, Li D, Yang D, Wei S, Su L, Ye T, Zheng X, Peng K, Zhang L, Zhang Y, Yang Y, Ma S. American journal of hypertension. 2016 29:63-72. (WB; Human) [Full Text Article] [PubMed:25958303] Related Antibodies: LS-C135684.
2
Commercially available angiotensin II At2 receptor antibodies are nonspecific. Hafko R, Villapol S, Nostramo R, Symes A, Sabban EL, Inagami T, Saavedra JM. PloS one. 8:e69234. [Full Text Article] [PubMed:23840911] [PMC:PMC3698141] Related Antibodies: LS-C11856.

☰ Filters
Products
ELISA Kits (14)
Competitive EIA (1)
Custom (2)
Sandwich (10)
Sandwich CLIA (1)
AGTR2 / AT2 Receptor (14)
Human (5)
Mouse (1)
Rat (3)
Chicken (1)
Monkey (1)
Porcine (1)
Rabbit (1)
Sheep (1)
12 x 8-Well Microstrips (1)
96-Well Microplate (1)
96-Well Strip Plate (12)
No (14)
Plasma (6)
Serum (6)
Tissue Homogenates (3)
AGTR2 / AT2 Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
AGTR2 / AT2 Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$728
AGTR2 / AT2 Receptor ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
AGTR2 / AT2 Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
AGTR2 / AT2 Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Sheep
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$760
AGTR2 / AT2 Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
AGTR2 / AT2 Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Porcine
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
AGTR2 / AT2 Receptor ELISA Kit
Select
Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$783
AGTR2 / AT2 Receptor ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$783
AGTR2 / AT2 Receptor ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
AGTR2 / AT2 Receptor ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Human
0.5 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
AGTR2 / AT2 Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
AGTR2 / AT2 Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
1 Plate/$818
AGTR2 / AT2 Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
1 Plate/$764
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).