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Unfortunately, the antibody (ID:64446) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



AGRN / Agrin

agrin

Isoform 1: heparan sulfate basal lamina glycoprotein that plays a central role in the formation and the maintenance of the neuromuscular junction (NMJ) and directs key events in postsynaptic differentiation. Component of the AGRN-LRP4 receptor complex that induces the phosphorylation and activation of MUSK. The activation of MUSK in myotubes induces the formation of NMJ by regulating different processes including the transcription of specific genes and the clustering of AChR in the postsynaptic membrane. Calcium ions are required for maximal AChR clustering. AGRN function in neurons is highly regulated by alternative splicing, glycan binding and proteolytic processing. Modulates calcium ion homestasis in neurons, specifically by inducing an increase in cytoplasmic calcium ions. Functions differentially in the central nervous system (CNS) by inhibiting the alpha(3)-subtype of Na+/K+-ATPase and evoking depolarization at CNS synapses. This secreted isoform forms a bridge, after release from motor neurons, to basal lamina through binding laminin via the NtA domain.Isoform 2: transmembrane form that is the predominate form in neurons of the brain, induces dendritic filopodia and synapse formation in mature hippocampal neurons in large part due to the attached glycosaminoglycan chains and the action of Rho-family GTPases.Isoform 1, isoform 4 and isoform 5: neuron-specific (z+) isoforms that contain C-terminal insertions of 8-19 AA are potent activators of AChR clustering. Isoform 5, agrin (z+8), containing the 8-AA insert, forms a receptor complex in myotubules containing the neuronal AGRN, the muscle-specific kinase MUSK and LRP4, a member of the LDL receptor family. The splicing factors, NOVA1 and NOVA2, regulate AGRN splicing and production of the 'z' isoforms.Isoform 3 and isoform 6: lack any 'z' insert, are muscle-specific and may be involved in endothelial cell differentiation.Agrin N-terminal 110 kDa subunit: is involved in regulation of neurite outgrowth probably due to the presence of the glycosaminoglcan (GAG) side chains of heparan and chondroitin sulfate attached to the Ser/Thr- and Gly/Ser-rich regions. Also involved in modulation of growth factor signaling.

Gene Name: agrin
Synonyms: AGRN, Agrin, Agrin proteoglycan
Target Sequences: NM_198576 AAC39776.1 O00468

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Target Reactivity Applications Host Isotype Clonality Clone Format Epitope Publications Type
AGRN / Agrin Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat IHC, ELISA N-Terminus No Primary
Anti-AGRN / Agrin Antibody (N-Terminus) LS-C137122
Immunohistochemistry Image
Rabbit Polyclonal (IgG) to Human AGRN / Agrin
Human, Mouse, Rat
IHC, ELISA
Unconjugated
AGRN / Agrin Rabbit IgG Polyclonal Biotin Conjugated Mouse IHC-P, IHC-Fr, ICC, WB, ELISA aa1130-1401 No Primary
Anti-AGRN / Agrin Antibody (aa1130-1401, Biotin) LS-C420273
Rabbit Polyclonal (IgG) to Mouse AGRN / Agrin
Mouse
IHC - Paraffin, IHC - Frozen, ICC, Western blot, ELISA
Biotin Conjugated
AGRN / Agrin Rabbit IgG Polyclonal FITC Conjugated Mouse IHC-P, IHC-Fr, ICC, WB, ELISA aa1130-1401 No Primary
Anti-AGRN / Agrin Antibody (aa1130-1401, FITC) LS-C420272
Rabbit Polyclonal (IgG) to Mouse AGRN / Agrin
Mouse
IHC - Paraffin, IHC - Frozen, ICC, Western blot, ELISA
FITC Conjugated
AGRN / Agrin Rabbit Polyclonal Unconjugated Mouse, Human, Rat IHC, WB, ELISA No Primary
Anti-AGRN / Agrin Antibody LS-C415018
Rabbit Polyclonal to Mouse AGRN / Agrin
Mouse, Human, Rat
IHC, Western blot, ELISA
Unconjugated
AGRN / Agrin Mouse IgG1 Monoclonal Unconjugated Rat, Mouse IHC-Fr, WB No Primary
Anti-AGRN / Agrin Antibody LS-C45609
Mouse Monoclonal (IgG1) to Rat AGRN / Agrin
Rat, Mouse
IHC - Frozen, Western blot
Unconjugated
AGRN / Agrin Rabbit IgG Polyclonal Unconjugated Human IHC, ELISA No Primary
Anti-AGRN / Agrin Antibody LS-C405862
Immunohistochemistry Image
Immunohistochemistry Image
Rabbit Polyclonal (IgG) to Human AGRN / Agrin
Human
IHC, ELISA
Unconjugated
AGRN / Agrin Rabbit IgG Polyclonal Unconjugated Human IHC, ELISA No Primary
Anti-AGRN / Agrin Antibody LS-C402607
Immunohistochemistry Image
Rabbit Polyclonal (IgG) to Human AGRN / Agrin
Human
IHC, ELISA
Unconjugated
AGRN / Agrin Mouse IgG1 Monoclonal Agr247 Unconjugated Rat, Mouse IHC C-Terminus No Primary
Anti-AGRN / Agrin Antibody (C-Terminus, clone Agr247) LS-C63142
Mouse Monoclonal [clone Agr247] (IgG1) to Rat AGRN / Agrin
Rat, Mouse
IHC
Unconjugated
AGRN / Agrin Mouse IgG1 Monoclonal Agr-33 Unconjugated Rat, Mouse IHC C-Terminus No Primary
Anti-AGRN / Agrin Antibody (C-Terminus, clone Agr-33) LS-C63140
Mouse Monoclonal [clone Agr-33] (IgG1) to Rat AGRN / Agrin
Rat, Mouse
IHC
Unconjugated
AGRN / Agrin Rabbit IgG Polyclonal Unconjugated Human WB, ELISA aa1856-2045 No Primary
Anti-AGRN / Agrin Antibody (aa1856-2045) LS-C314746
Western blot Image
Rabbit Polyclonal (IgG) to Human AGRN / Agrin
Human
Western blot, ELISA
Unconjugated
AGRN / Agrin Rabbit IgG Polyclonal Unconjugated Rat WB, ELISA aa1206-1475 No Primary
Anti-AGRN / Agrin Antibody (aa1206-1475) LS-C314745
Western blot Image
Rabbit Polyclonal (IgG) to Rat AGRN / Agrin
Rat
Western blot, ELISA
Unconjugated
AGRN / Agrin Rabbit IgG Polyclonal FITC Conjugated Rat ICC, WB, ELISA aa1206-1475 No Primary
Anti-AGRN / Agrin Antibody (aa1206-1475, FITC) LS-C420274
Rabbit Polyclonal (IgG) to Rat AGRN / Agrin
Rat
ICC, Western blot, ELISA
FITC Conjugated
AGRN / Agrin Rabbit IgG Polyclonal Biotin Conjugated Rat ICC, WB, ELISA aa1206-1475 No Primary
Anti-AGRN / Agrin Antibody (aa1206-1475, Biotin) LS-C420275
Rabbit Polyclonal (IgG) to Rat AGRN / Agrin
Rat
ICC, Western blot, ELISA
Biotin Conjugated
AGRN / Agrin Rabbit IgG Polyclonal Biotin Conjugated Human ICC, WB, ELISA aa1856-2045 No Primary
Anti-AGRN / Agrin Antibody (aa1856-2045, Biotin) LS-C420270
Rabbit Polyclonal (IgG) to Human AGRN / Agrin
Human
ICC, Western blot, ELISA
Biotin Conjugated
AGRN / Agrin Rabbit IgG Polyclonal FITC Conjugated Human ICC, WB, ELISA aa1856-2045 No Primary
Anti-AGRN / Agrin Antibody (aa1856-2045, FITC) LS-C420271
Rabbit Polyclonal (IgG) to Human AGRN / Agrin
Human
ICC, Western blot, ELISA
FITC Conjugated
AGRN / Agrin Rabbit IgG Polyclonal Unconjugated Mouse WB, ELISA aa1130-1401 No Primary
Anti-AGRN / Agrin Antibody (aa1130-1401) LS-C374094
Western blot Image
Rabbit Polyclonal (IgG) to Mouse AGRN / Agrin
Mouse
Western blot, ELISA
Unconjugated
AGRN / Agrin Mouse IgG2a Monoclonal AGR 131 Unconjugated Rat, Mouse WB C-Terminus No Primary
Anti-AGRN / Agrin Antibody (C-Terminus, clone AGR 131) LS-C63141
Mouse Monoclonal [clone AGR 131] (IgG2a) to Rat AGRN / Agrin
Rat, Mouse
Western blot
Unconjugated
AGRN / Agrin Rabbit Polyclonal Unconjugated Human, Mouse, Rat WB C-Terminus No Primary
Anti-AGRN / Agrin Antibody (C-Terminus) LS-C353868
Western blot Image
Rabbit Polyclonal to Human AGRN / Agrin
Human, Mouse, Rat
Western blot
Unconjugated
AGRN / Agrin Rabbit Polyclonal Unconjugated Human, Mouse, Rat WB No Primary
Anti-AGRN / Agrin Antibody LS-C342124
Rabbit Polyclonal to Human AGRN / Agrin
Human, Mouse, Rat
Western blot
Unconjugated
AGRN / Agrin Mouse IgG1 Monoclonal Unconjugated Rat, Mouse ICC, WB C-Terminus No Primary
Anti-AGRN / Agrin Antibody (C-Terminus) LS-C63821
Mouse Monoclonal (IgG1) to Rat AGRN / Agrin
Rat, Mouse
ICC, Western blot
Unconjugated
AGRN / Agrin Mouse IgG1 Monoclonal Unconjugated Rat, Mouse ICC, WB C-Terminus No Primary
Anti-AGRN / Agrin Antibody (C-Terminus) LS-C11825
Mouse Monoclonal (IgG1) to Rat AGRN / Agrin
Rat, Mouse
ICC, Western blot
Unconjugated
AGRN / Agrin Mouse IgG2a Monoclonal Unconjugated Rat, Mouse ICC, WB C-Terminus No Primary
Anti-AGRN / Agrin Antibody (C-Terminus) LS-C11829
Mouse Monoclonal (IgG2a) to Rat AGRN / Agrin
Rat, Mouse
ICC, Western blot
Unconjugated
Type Target Reactivity Sample Type
Sandwich (Custom) AGRN / Agrin Rat Cell Culture Supernatants, Serum, Plasma
Rat AGRN / Agrin ELISA Kit (Sandwich ELISA) (Custom) - LS-F404
 Image
 Image
Quantitative Sandwich ELISA
96-Well Microplate
Rat
0.205-20 ng/ml
Colorimetric - 450nm
Cell Culture Supernatants, Serum, Plasma
Sandwich AGRN / Agrin Human Serum, Tissue Homogenates, Plasma
Human AGRN / Agrin ELISA Kit (Sandwich ELISA) - LS-F4549
 Image
 Image
Sandwich ELISA
96-Well Strip Plate
Human
31.25-2000 pg/ml
Colorimetric - 450nm
Serum, Tissue Homogenates, Plasma
Sandwich AGRN / Agrin Human Cell Culture Supernatants, Serum, Tissue Homogenates, Plasma
Human AGRN / Agrin ELISA Kit (Sandwich ELISA) - LS-F10767
 Image
 Image
Quantitative Sandwich ELISA
96-Well Strip Plate
Human
0.156-10 ng/ml
Cell Culture Supernatants, Serum, Tissue Homogenates, Plasma
Sandwich (Custom) AGRN / Agrin Mouse
Mouse AGRN / Agrin ELISA Kit (Sandwich ELISA) (Custom) - LS-F16819
 Image
 Image
Sandwich ELISA
96-Well Strip Plate
Mouse
Sandwich (Custom) AGRN / Agrin Chicken
Chicken AGRN / Agrin ELISA Kit (Sandwich ELISA) (Custom) - LS-F16820
 Image
 Image
Sandwich ELISA
96-Well Strip Plate
Chicken
Sandwich (Custom) AGRN / Agrin Rat
Rat AGRN / Agrin ELISA Kit (Sandwich ELISA) (Custom) - LS-F16821
 Image
 Image
Sandwich ELISA
96-Well Strip Plate
Rat
Sandwich AGRN / Agrin Human Serum, Plasma
Human AGRN / Agrin ELISA Kit (Sandwich ELISA) - LS-F20883
 Image
 Image
Quantitative Sandwich ELISA
96-Well Microplate
Human
0.156-10 ng/ml
Colorimetric - 450nm
Serum, Plasma
Sandwich AGRN / Agrin Rat Serum, Plasma
Rat AGRN / Agrin ELISA Kit (Sandwich ELISA) - LS-F23619
 Image
 Image
Quantitative Sandwich ELISA
96-Well Microplate
Rat
31.25-2000 pg/ml
Colorimetric - 450nm
Serum, Plasma
Sandwich AGRN / Agrin Human Cell Culture Supernatants, Serum, Tissue Homogenates, Plasma
Human AGRN / Agrin ELISA Kit (Sandwich ELISA) - LS-F26644
 Image
 Image
Quantitative Sandwich ELISA
96-Well Strip Plate
Human
0.5-10 ng/ml
Colorimetric - 450nm
Cell Culture Supernatants, Serum, Tissue Homogenates, Plasma
Type Target Tag Species Source Purified Biological Activity Known Endotoxin Level Animal-Free
Recombinant AGRN / Agrin His + T7 Human E. coli
Human AGRN / Agrin Recombinant (His + T7) Protein - LS-G13615
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
E. coli Expression System
His + T7
Unpurified
Recombinant AGRN / Agrin His + T7 Rat E. coli
Rat AGRN / Agrin Recombinant (His + T7) Protein - LS-G13616
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
E. coli Expression System
His + T7
Unpurified
Recombinant AGRN / Agrin His + S Mouse E. coli
Mouse AGRN / Agrin Recombinant (His + S) Protein - LS-G24268
E. coli Expression System
His + S
Unpurified

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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