AGO3 / EIF2C3

argonaute RISC catalytic component 3

Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Proposed to be involved in stabilization of small RNA derivates (riRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent riRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4.

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Products

Proteins (8)

Type

Over-Expression Lysate (4)

Recombinant (4)

Target

AGO3 / EIF2C3 (8)

Publications

No (8)

Tag

GST (1)

GST, N-terminus (1)

His,N-terminus (1)

Myc-DDK (Flag) (5)

Species

Human (6)

Source

293T Cells (2)

HEK 293 Cells (3)

Insect Cells (1)

Wheat Germ Extract (2)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (1)

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Human AGO3 / EIF2C3 Protein (Recombinant His,N-terminus) (Met1-Ala860) - LS-G138403

Source:

Insect Cells

Tag:

His,N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

99.6 kDa

Price:

20 µg/$600

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Human AGO3 / EIF2C3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88366

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

71 kDa

Price:

20 µg/$215

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Human AGO3 / EIF2C3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88365

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

97.2 kDa

Price:

20 µg/$215

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AGO3 / EIF2C3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G109712

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

97.2 kDa

Price:

100 µg/$710

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AGO3 / EIF2C3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G104901

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

71 kDa

Price:

100 µg/$710

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Human AGO3 / EIF2C3 Protein (Recombinant GST) (Full Length) - LS-G36919

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

97.6 kDa

Price:

2 µg/$439

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Human AGO3 / EIF2C3 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70939

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

97.2 kDa

Price:

20 µg/$1,107

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Human AGO3 / EIF2C3 Protein (Recombinant GST, N-terminus) (aa1-100) - LS-G64595

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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