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Unfortunately, the antibody (ID:132335) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



AGO2 / EIF2C2

argonaute RISC catalytic component 2

Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the mRNA specifically by AGO2. Binding of RISC to a partially complementary mRNA results in silencing through inhibition of translation, and this is independent of endonuclease activity. May inhibit translation initiation by binding to the 7-methylguanosine cap, thereby preventing the recruitment of the translation initiation factor eIF4-E. May also inhibit translation initiation via interaction with EIF6, which itself binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit. The inhibition of translational initiation leads to the accumulation of the affected mRNA in cytoplasmic processing bodies (P-bodies), where mRNA degradation may subsequently occur. In some cases RISC-mediated translational repression is also observed for miRNAs that perfectly match the 3' untranslated region (3'-UTR). Can also up-regulate the translation of specific mRNAs under certain growth conditions. Binds to the AU element of the 3'-UTR of the TNF (TNF-alpha) mRNA and up-regulates translation under conditions of serum starvation. Also required for transcriptional gene silencing (TGS), in which short RNAs known as antigene RNAs or agRNAs direct the transcriptional repression of complementary promoter regions.

Gene Name: argonaute RISC catalytic component 2
Synonyms: AGO2, Argonaute2, Argonaute 2, EIF-2C 2, EIF2C2, EIF2C 2, HAgo2, PPD, Protein slicer, Q10, PAZ Piwi domain protein, Protein argonaute-2
Target Sequences: AF121255 AAF13034.2

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Target Reactivity Applications Host Isotype Clonality Clone Format Epitope Publications Type
AGO2 / EIF2C2 Mouse IgG1,k Monoclonal 2E12-1C9 Unconjugated Human IHC-P, IF, WB, ELISA
1
AGO2 / EIF2C2 Mouse IgG1,k Monoclonal 2E12-1C9 Unconjugated Human IHC-P, IF, WB, ELISA No Primary
Anti-AGO2 / EIF2C2 Antibody (clone 2E12-1C9) IHC-plus™ LS-B6224
Immunohistochemistry Image
Immunofluorescence Image


Mouse Monoclonal [clone 2E12-1C9] (IgG1,k) to Human AGO2 / EIF2C2
Human
IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Unconjugated
AGO2 / EIF2C2 Rabbit IgG Polyclonal Unconjugated,HRP Conjugated, Azide-free,Biotin Conjugated,FITC Conjugated,APC Conjugated,AP Conjugated,PE Conjugated Human IHC, WB, Flo, ELISA,IHC, WB, Flo, ELISA,IHC, WB, Flo, ELISA,IHC, WB, Flo, ELISA,IHC, WB, Flo, ELISA,IHC, WB, Flo, ELISA,IHC, WB, Flo, ELISA N-Terminus
7
AGO2 / EIF2C2 Rabbit IgG Polyclonal Unconjugated Human IHC, WB, Flo, ELISA N-Terminus No Primary
Anti-AGO2 / EIF2C2 Antibody (N-Terminus) LS-C329490


Rabbit Polyclonal (IgG) to Human AGO2 / EIF2C2
Human
IHC, Western blot, Flow Cytometry, ELISA
Unconjugated
AGO2 / EIF2C2 Rabbit IgG Polyclonal HRP Conjugated, Azide-free Human IHC, WB, Flo, ELISA N-Terminus No Primary
Anti-AGO2 / EIF2C2 Antibody (N-Terminus, Azide-free, HRP) LS-C222374


Rabbit Polyclonal (IgG) to Human AGO2 / EIF2C2
Human
IHC, Western blot, Flow Cytometry, ELISA
HRP Conjugated, Azide-free
AGO2 / EIF2C2 Rabbit IgG Polyclonal Biotin Conjugated Human IHC, WB, Flo, ELISA N-Terminus No Primary
Anti-AGO2 / EIF2C2 Antibody (N-Terminus, Biotin) LS-C222372


Rabbit Polyclonal (IgG) to Human AGO2 / EIF2C2
Human
IHC, Western blot, Flow Cytometry, ELISA
Biotin Conjugated
AGO2 / EIF2C2 Rabbit IgG Polyclonal FITC Conjugated Human IHC, WB, Flo, ELISA N-Terminus No Primary
Anti-AGO2 / EIF2C2 Antibody (N-Terminus, FITC) LS-C222373


Rabbit Polyclonal (IgG) to Human AGO2 / EIF2C2
Human
IHC, Western blot, Flow Cytometry, ELISA
FITC Conjugated
AGO2 / EIF2C2 Rabbit IgG Polyclonal APC Conjugated Human IHC, WB, Flo, ELISA N-Terminus No Primary
Anti-AGO2 / EIF2C2 Antibody (N-Terminus, APC) LS-C222370


Rabbit Polyclonal (IgG) to Human AGO2 / EIF2C2
Human
IHC, Western blot, Flow Cytometry, ELISA
APC Conjugated
AGO2 / EIF2C2 Rabbit IgG Polyclonal AP Conjugated Human IHC, WB, Flo, ELISA N-Terminus No Primary
Anti-AGO2 / EIF2C2 Antibody (N-Terminus, AP) LS-C222371


Rabbit Polyclonal (IgG) to Human AGO2 / EIF2C2
Human
IHC, Western blot, Flow Cytometry, ELISA
AP Conjugated
AGO2 / EIF2C2 Rabbit IgG Polyclonal PE Conjugated Human IHC, WB, Flo, ELISA N-Terminus No Primary
Anti-AGO2 / EIF2C2 Antibody (N-Terminus, PE) LS-C222375


Rabbit Polyclonal (IgG) to Human AGO2 / EIF2C2
Human
IHC, Western blot, Flow Cytometry, ELISA
PE Conjugated
AGO2 / EIF2C2 Rabbit Polyclonal Unconjugated Human, Mouse, Rat WB, ELISA
1
AGO2 / EIF2C2 Rabbit Polyclonal Unconjugated Human, Mouse, Rat WB, ELISA No Primary
Anti-AGO2 / EIF2C2 Antibody LS-C136915
Western blot Image


Rabbit Polyclonal to Human AGO2 / EIF2C2
Human, Mouse, Rat
Western blot, ELISA
Unconjugated
AGO2 / EIF2C2 Rabbit IgG Polyclonal Unconjugated,HRP Conjugated,Biotin Conjugated,FITC Conjugated Human IHC-P, ELISA, ChrIP,IHC, IHC-P, ELISA, ChrIP,IHC, IHC-P, ELISA, ChrIP,IHC, IHC-P, ELISA, ChrIP aa517-818
4
AGO2 / EIF2C2 Rabbit IgG Polyclonal Unconjugated Human IHC-P, ELISA, ChrIP aa517-818 No Primary
Anti-AGO2 / EIF2C2 Antibody (aa517-818) LS-C372287
Immunohistochemistry Image


Rabbit Polyclonal (IgG) to Human AGO2 / EIF2C2
Human
IHC - Paraffin, ELISA, Chromatin Immunoprecipitation
Unconjugated
AGO2 / EIF2C2 Rabbit IgG Polyclonal HRP Conjugated Human IHC, IHC-P, ELISA, ChrIP aa517-818 No Primary
Anti-AGO2 / EIF2C2 Antibody (aa517-818, HRP) LS-C372289
Immunohistochemistry Image


Rabbit Polyclonal (IgG) to Human AGO2 / EIF2C2
Human
IHC, IHC - Paraffin, ELISA, Chromatin Immunoprecipitation
HRP Conjugated
AGO2 / EIF2C2 Rabbit IgG Polyclonal Biotin Conjugated Human IHC, IHC-P, ELISA, ChrIP aa517-818 No Primary
Anti-AGO2 / EIF2C2 Antibody (aa517-818, Biotin) LS-C372291
Immunohistochemistry Image


Rabbit Polyclonal (IgG) to Human AGO2 / EIF2C2
Human
IHC, IHC - Paraffin, ELISA, Chromatin Immunoprecipitation
Biotin Conjugated
AGO2 / EIF2C2 Rabbit IgG Polyclonal FITC Conjugated Human IHC, IHC-P, ELISA, ChrIP aa517-818 No Primary
Anti-AGO2 / EIF2C2 Antibody (aa517-818, FITC) LS-C372290
Immunohistochemistry Image


Rabbit Polyclonal (IgG) to Human AGO2 / EIF2C2
Human
IHC, IHC - Paraffin, ELISA, Chromatin Immunoprecipitation
FITC Conjugated
AGO2 / EIF2C2 Rabbit IgG Polyclonal Unconjugated Human, Bovine, Pig, Rabbit WB aa498-812
1
AGO2 / EIF2C2 Rabbit IgG Polyclonal Unconjugated Human, Bovine, Pig, Rabbit WB aa498-812 No Primary
Anti-AGO2 / EIF2C2 Antibody (aa498-812) LS-C311886


Rabbit Polyclonal (IgG) to Human AGO2 / EIF2C2
Human, Bovine, Pig, Rabbit
Western blot
Unconjugated
AGO2 / EIF2C2 Rabbit IgG Polyclonal Unconjugated Human, Mouse IHC, WB
1
AGO2 / EIF2C2 Rabbit IgG Polyclonal Unconjugated Human, Mouse IHC, WB No Primary
Anti-AGO2 / EIF2C2 Antibody LS-C334953
Immunohistochemistry Image
Immunohistochemistry Image


Rabbit Polyclonal (IgG) to Human AGO2 / EIF2C2
Human, Mouse
IHC, Western blot
Unconjugated
AGO2 / EIF2C2 Mouse Monoclonal Unconjugated Human IF, IP
1
AGO2 / EIF2C2 Mouse Monoclonal Unconjugated Human IF, IP No Primary
Anti-AGO2 / EIF2C2 Antibody LS-C497867


Mouse Monoclonal to Human AGO2 / EIF2C2
Human
Immunofluorescence, Immunoprecipitation
Unconjugated
AGO2 / EIF2C2 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat IHC, ELISA
1
AGO2 / EIF2C2 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat IHC, ELISA No Primary
Anti-AGO2 / EIF2C2 Antibody LS-C401199
Immunohistochemistry Image


Rabbit Polyclonal (IgG) to Human AGO2 / EIF2C2
Human, Mouse, Rat
IHC, ELISA
Unconjugated
AGO2 / EIF2C2 Rabbit Polyclonal Unconjugated Human, Mouse, Rat WB, ELISA
1
AGO2 / EIF2C2 Rabbit Polyclonal Unconjugated Human, Mouse, Rat WB, ELISA No Primary
Anti-AGO2 / EIF2C2 Antibody LS-C415312
Western blot Image


Rabbit Polyclonal to Human AGO2 / EIF2C2
Human, Mouse, Rat
Western blot, ELISA
Unconjugated
AGO2 / EIF2C2 Rabbit Polyclonal Unconjugated Human, Mouse, Rat WB, ELISA
1
AGO2 / EIF2C2 Rabbit Polyclonal Unconjugated Human, Mouse, Rat WB, ELISA No Primary
Anti-AGO2 / EIF2C2 Antibody LS-C413766
Western blot Image


Rabbit Polyclonal to Human AGO2 / EIF2C2
Human, Mouse, Rat
Western blot, ELISA
Unconjugated
AGO2 / EIF2C2 Rabbit IgG Polyclonal Unconjugated Human ELISA
1
AGO2 / EIF2C2 Rabbit IgG Polyclonal Unconjugated Human ELISA No Primary
Anti-AGO2 / EIF2C2 Antibody LS-C69256


Rabbit Polyclonal (IgG) to Human AGO2 / EIF2C2
Human
ELISA
Unconjugated
AGO2 / EIF2C2 Rabbit Polyclonal Unconjugated Mouse
1
AGO2 / EIF2C2 Rabbit Polyclonal Unconjugated Mouse No Primary
Anti-AGO2 / EIF2C2 Antibody LS-C483261


Rabbit Polyclonal to Mouse AGO2 / EIF2C2
Mouse
Unconjugated
AGO2 / EIF2C2 Rabbit Polyclonal Unconjugated Mouse
1
AGO2 / EIF2C2 Rabbit Polyclonal Unconjugated Mouse No Primary
Anti-AGO2 / EIF2C2 Antibody LS-C483260


Rabbit Polyclonal to Mouse AGO2 / EIF2C2
Mouse
Unconjugated
AGO2 / EIF2C2 Rabbit Polyclonal Unconjugated Human
1
AGO2 / EIF2C2 Rabbit Polyclonal Unconjugated Human No Primary
Anti-AGO2 / EIF2C2 Antibody LS-C483391


Rabbit Polyclonal to Human AGO2 / EIF2C2
Human
Unconjugated
AGO2 / EIF2C2 Rabbit Polyclonal Unconjugated Human
1
AGO2 / EIF2C2 Rabbit Polyclonal Unconjugated Human No Primary
Anti-AGO2 / EIF2C2 Antibody LS-C483389


Rabbit Polyclonal to Human AGO2 / EIF2C2
Human
Unconjugated
Type Target Reactivity Sample Type
Sandwich AGO2 / EIF2C2 Human Cell Culture Supernatants, Serum, Tissue Homogenates, Plasma
1
Human AGO2 / EIF2C2 ELISA Kit (Sandwich ELISA) - LS-F16185
 Image
 Image


Sandwich ELISA
96-Well Strip Plate
Human
31.2-2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Serum, Tissue Homogenates, Plasma
Sandwich AGO2 / EIF2C2 Mouse Cell Culture Supernatants, Serum, Tissue Homogenates, Plasma
1
Mouse AGO2 / EIF2C2 ELISA Kit (Sandwich ELISA) - LS-F16187
 Image
 Image


Sandwich ELISA
96-Well Strip Plate
Mouse
31.2-2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Serum, Tissue Homogenates, Plasma
Sandwich AGO2 / EIF2C2 Bovine Cell Culture Supernatants, Serum, Tissue Homogenates, Plasma
1
Bovine AGO2 / EIF2C2 ELISA Kit (Sandwich ELISA) - LS-F10766
 Image
 Image


Quantitative Sandwich ELISA
96-Well Strip Plate
Bovine
15.6-1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Serum, Tissue Homogenates, Plasma
Custom AGO2 / EIF2C2 Rat
1
Rat AGO2 / EIF2C2 ELISA Kit (Custom ELISA) - LS-F16186
 Image
 Image


Custom ELISA
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
Type Target Tag Species Source Purified Biological Activity Known Endotoxin Level Animal-Free
AGO2 / EIF2C2 None Baculovirus Insect Purified Has biological activity Known endotoxin level
1
Baculovirus AGO2 / EIF2C2 Protein (Met1-Ala859) - LS-G48324


Insect Baculovirus
None
Purified / Lyophilized / Biologically Active / Endotoxin Level: Less than 1.0 EU/µg protein (determined by LAL method).
Met 1-Ala 859
Recombinant AGO2 / EIF2C2 His Human E. coli
1
Human AGO2 / EIF2C2 Protein (Recombinant His) (aa517-818) - LS-G22005
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image


E. coli Expression System
302 AA
His
aa 517-818
38.1 kD
Recombinant AGO2 / EIF2C2 His Human Yeast
1
Human AGO2 / EIF2C2 Protein (Recombinant His) (aa517-818) - LS-G23479
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image


Yeast Expression System
302 AA
His
aa 517-818
36 kD
Recombinant AGO2 / EIF2C2 GST Human Wheat Purified
1
Human AGO2 / EIF2C2 Protein (Recombinant GST) - LS-G33281
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image


Wheat Wheat Germ Extract
377 AA
GST
Purified
68.8 kDa
Recombinant AGO2 / EIF2C2 GST Human Wheat Purified
1
Human AGO2 / EIF2C2 Protein (Recombinant GST) - LS-G33282
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image


Wheat Wheat Germ Extract
377 AA
GST
Purified
68.03 kDa
Selected:

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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