AGL

amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase

Glycogen debranching enzyme is involved in glycogen degradation and has two independent catalytic activities: a 4-alpha-glucotransferase activity (EC 2.4.1.25) and a amylo-1,6-glucosidase activity (EC 3.4.1.33). Both activities occur at different sites on the single polypeptide chain. Mutations in this gene cause glycogen storage disease. A wide range of clinical and enzymatic variability occurs in glycogen debrancher deficiency, some of which may be due to tissue-specific alternative splicing. Six splice variants that differ in the 5' end have been identified in liver and muscle tissue. Variants 1, 5, and 6 are present in both liver and muscle, whereas variants 2, 3, and 4 occur in muscle. Variants 1 through 4 encode identical proteins (isoform 1) that include 27 N-terminal amino acids not found in splice variants 5 and 6. Variants 5 and 6 encode different amino-terminal ends of 10 and 11 amino acids in protein isoforms 2 and 3, respectively, with the remainder of the peptide identical to that of isoforms 1.

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Products

Proteins (12)

Type

Over-Expression Lysate (8)

Recombinant (4)

Target

AGL (12)

Publications

No (12)

Tag

His-T7, N-terminus (1)

Myc-DDK (Flag) (11)

Species

Human (8)

Source

293T Cells (4)

E. coli (1)

HEK 293 Cells (7)

Purification

Purified (1)

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AGL Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G123062

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

174.6 kDa

Price:

100 µg/$494

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AGL Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G123063

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

174.6 kDa

Price:

100 µg/$710

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AGL Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G123064

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

174.6 kDa

Price:

100 µg/$710

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AGL Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G123441

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

174.6 kDa

Price:

100 µg/$494

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Human AGL Protein (Recombinant His-T7, N-terminus) (Met1167-Leu1532) - LS-G133287

Source:

E. coli

Tag:

His-T7, N-terminus

Molecular Weight:

45.5kDa

Price:

10 µg/$267; 50 µg/$352; 200 µg/$702; 100 µg/$562; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900

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Human AGL Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76227

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

174.6 kDa

Price:

20 µg/$150

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Human AGL Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76228

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

174.6 kDa

Price:

20 µg/$150

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Human AGL Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76231

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

174.6 kDa

Price:

20 µg/$215

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Human AGL Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76233

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

174.6 kDa

Price:

20 µg/$215

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Human AGL Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65758

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

174.6 kDa

Price:

20 µg/$1,107

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Human AGL Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65759

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

174.6 kDa

Price:

20 µg/$1,107

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Human AGL Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65760

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

174.6 kDa

Price:

20 µg/$1,107

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