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Required for vesicle docking or fusion during acrosome biogenesis (By similarity). May play a role in RNA trafficking or localization. In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element-containing RNAs from the nuclear periphery to the cytoplasm. This step is essential for HIV-1 replication.
Gene Name: | ArfGAP with FG repeats 1 |
Synonyms: | AGFG1, HRIP, Rev interacting protein, HIV-1 Rev binding protein, HIV-1 Rev-binding protein, HRB, Rev-interacting protein, RIP, Nucleoporin-like protein RIP, RAB, ArfGAP with FG repeats 1 |
Target Sequences: | NM_004504 NP_004495.2 P52594 |
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