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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
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Unfortunately, the antibody (ID:194211) is no longer available.
Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page.
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adrenoceptor beta 2, surface
ADRB2 is beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.
Matrix metalloproteinases cleave the beta2-adrenergic receptor in spontaneously hypertensive rats. Rodrigues SF, Tran ED, Fortes ZB, Schmid-Schnbein GW. American journal of physiology. Heart and circulatory physiology. 2010 299:H25-35.
ß-Adrenergic receptor subtype expression in myocyte and non-myocyte cells in human female bladder. Limberg BJ, Andersson KE, Aura Kullmann F, Burmer G, de Groat WC, Rosenbaum JS. Cell and tissue research. 2011 317:107-16. (ICC, IHC-P; Human)[Full Text Article]
Related Antibodies: LS-A2662.
Clenbuterol and formoterol decrease force production in isolated intact mouse skeletal muscle fiber bundles through a beta2-adrenoceptor-independent mechanism. McCormick C, Alexandre L, Thompson J, Mutungi G. Journal of applied physiology (Bethesda, Md. : 1985). 2010 Dec;109:1716-27. [Full Text Article]
Related Antibodies: LS-C54456.