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Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling.
Gene Name: | adrenoceptor beta 1 |
Family/Subfamily: | GPCR , Adrenergic |
Synonyms: | ADRB1, Adrenoceptor beta 1, Beta1-adrenergic receptor, Beta-1 adrenergic receptor, Beta1-adrenoceptor, B1AR, Beta-1 adrenoceptor, Beta-1 adrenoreceptor, BETA1AR, ADRB1R, Adrenergic, beta-1-, receptor, RHR |
Target Sequences: | NM_000684 NP_000675.1 P08588 |
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