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ADRA1A
adrenoceptor alpha 1A
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties.
| Gene Name: | adrenoceptor alpha 1A |
| Family/Subfamily: | GPCR , Adrenergic |
| Synonyms: | ADRA1A, ADRA1L1, Adrenergic alpha 1c receptor, Alpha 1c adrenoceptor, Alpha-adrenergic receptor 1c, ADRA1C, Adrenoceptor alpha 1A, Alpha-1A adrenoceptor, Alpha-1A adrenoreceptor, Alpha-1A adrenergic receptor, Alpha-1C adrenergic receptor, ALPHA1AAR, Alpha1C-AR |
| Target Sequences: | NM_000680 BAA04960.1 P35348 |
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