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ADH1A / Alcohol Dehydrogenase

alcohol dehydrogenase 1A (class I), alpha polypeptide

ADH1A / Alcohol Dehydrogenase encodes a member of the alcohol dehydrogenase family. The encoded protein is the alpha subunit of class I alcohol dehydrogenase, which consists of several homo- and heterodimers of alpha, beta and gamma subunits. Alcohol dehydrogenases catalyze the oxidation of alcohols to aldehydes. This gene is active in the liver in early fetal life but only weakly active in adult liver. This gene is found in a cluster with six additional alcohol dehydrogenase genes, including those encoding the beta and gamma subunits, on the long arm of chromosome 4. Mutations in this gene may contribute to variation in certain personality traits and substance dependence.

Gene Name: alcohol dehydrogenase 1A (class I), alpha polypeptide
Synonyms: ADH1A, ADH1, ADH, alpha subunit, Aldehyde reductase, Alcohol dehydrogenase, Alcohol dehydrogenase 1A
Target Sequences: NM_000667 NP_000658.1 P07327

Publications (1)

1
Whole genome sequencing data and analyses of the underlying SUP35 transcriptional regulation for a Saccharomyces cerevisiae nonsense suppressor mutant. Matveenko AG, Drozdova PB, Moskalenko SE, Tarasov OV, Zhouravleva GA. Data in brief. 2019 January;23:103694. [Full Text Article] [PubMed:30788402] [PMC:PMC6369104]

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Proteins (7)
Over-Expression Lysate (2)
Recombinant (5)
ADH1A / Alcohol Dehydrogenase (7)
No (7)
GST, N-terminus (1)
His (1)
His-T7 (2)
Myc-DDK (Flag) (3)
Human (5)
Mouse (1)
293T Cells (1)
E. coli (3)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
ADH1A / Alcohol Dehydrogenase Protein - Purified recombinant protein ADH1A was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
39.7 kDa
20 µg/$1,107
ADH1A / Alcohol Dehydrogenase Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
2 µg/$439
ADH1A / Alcohol Dehydrogenase Protein - Recombinant Alcohol Dehydrogenase 1 By SDS-PAGE
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E. coli
His-T7
25.1 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
ADH1A / Alcohol Dehydrogenase Protein - Recombinant Alcohol Dehydrogenase 1 By SDS-PAGE
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E. coli
His-T7
24.9 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
ADH1A / Alcohol Dehydrogenase Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
39.7 kDa
100 µg/$494
ADH1A / Alcohol Dehydrogenase Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
ADH1A / Alcohol Dehydrogenase Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
39.7 kDa
20 µg/$150
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).