ADGRB1 / BAI1

brain-specific angiogenesis inhibitor 1

Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis and a growth suppressor of glioblastomas

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Proteins (2)

Type

Over-Expression Lysate (2)

Target

ADGRB1 / BAI1 (2)

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No (2)

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Myc-DDK (Flag) (2)

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Human (1)

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293T Cells (1)

HEK 293 Cells (1)

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ADGRB1 / BAI1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118455

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

173.5 kDa

Price:

100 µg/$710

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Human ADGRB1 / BAI1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79806

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

173.5 kDa

Price:

20 µg/$215

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