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ADGRB1 / BAI1

brain-specific angiogenesis inhibitor 1

Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis and a growth suppressor of glioblastomas

Gene Name: brain-specific angiogenesis inhibitor 1
Family/Subfamily: GPCR , Orphan-B
Synonyms: ADGRB1, BAI1, GDAIF
Target Sequences: NM_001702 BAA23647.1 O14514

Publications (1)

1
Phagocytosing differentiated cell-fragments is a novel mechanism for controlling somatic stem cell differentiation within a short time frame. Shohei Wakao, Yo Oguma, Yoshihiro Kushida, Yasumasa Kuroda, Kazuki Tatsumi, Mari Dezawa. Cellular and molecular life sciences : CMLS. 2022 October;79:542. [Full Text Article] [PubMed:36203068] [PMC:PMC9537123] Related Antibodies: LS-C177193.

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Antibodies (29)
Primary (29)
ADGRB1 / BAI1 (29)
Human (27)
Mouse (18)
Rat (4)
Bovine (2)
Chicken (1)
Hamster (1)
Monkey (5)
IHC (27)
IHC-P (14)
WB (10)
ELISA (12)
ICC (1)
IF (6)
Peptide-ELISA (3)
rabbit (28)
rabbit-new zealand white (1)
Product Group
GPCR Database Antibodies (4)
IHCPlus (5)
IgG (15)
polyclonal pc (29)
APC Conjugated (1)
Biotin Conjugated (2)
DY488 Conjugated (1)
DY550 Conjugated (1)
DY650 Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (20)
C-Terminus (15)
670-750 aa, Internal (1)
Gln732 (1)
Internal (1)
N-Terminus (1)
aa60-350 (1)
aa683-732 (1)
aa691-740 (1)
No (28)
Yes (1)
ADGRB1 / BAI1 Antibody - Anti-BAI1 antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Chicken, Bovine, Rat, Hamster, Mouse, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
ADGRB1 / BAI1 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
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ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Bovine, Human, Monkey
ELISA, IHC, IHC-P
Unconjugated
50 µg/$440
ADGRB1 / BAI1 Antibody - Immunohistochemistry analysis of paraffin-embedded human brain tissue, using BAI1 Antibody. The picture on the right is blocked with the synthesized peptide.
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ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (aa691-740) Antibody
Mouse, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
ADGRB1 / BAI1 Antibody - IHC of BAI-1 (Q732) pAb in paraffin-embedded human brain.
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ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (Gln732) Antibody
Mouse, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
ADGRB1 / BAI1 Antibody - Immunohistochemistry of paraffin-embedded human brain tissue at dilution 1:100
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ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (aa60-350) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
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ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (670-750 aa, Internal) Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ADGRB1 / BAI1 Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
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ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (aa683-732) Antibody
Mouse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100 µl/$515
ADGRB1 / BAI1 Antibody - Immunohistochemical analysis of BAI1 staining in rat brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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ADGRB1 / BAI1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$321
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ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
IHC
Unconjugated
400 µl/$393
ADGRB1 / BAI1 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human brain tissue using BAI1 antibody.
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ADGRB1 / BAI1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
ADGRB1 / BAI1 Antibody - 1:100 staining human urothelial carcinoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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ADGRB1 / BAI1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ADGRB1 / BAI1 Antibody - Anti-BAI1 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
ADGRB1 / BAI1 Antibody - Anti-BAI1 antibody IHC of human brain, neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
ADGRB1 / BAI1 Antibody - Immunofluorescent analysis of BAI1 staining in HepG2 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 ??C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
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ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Human, Monkey
ICC, IF, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
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ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, IHC
Unconjugated
200 µl/$734
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ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Human
ELISA, IHC
HRP Conjugated
200 µl/$952
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ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Human
ELISA, IHC
Biotin Conjugated
200 µl/$952
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ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Human
ELISA, IHC
FITC Conjugated
200 µl/$952
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ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (C-Terminus) (APC) Antibody
Human
ELISA, IHC
APC Conjugated
200 µl/$952
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ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (C-Terminus) (PE) Antibody
Human
ELISA, IHC
PE Conjugated
200 µl/$952
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ADGRB1 / BAI1 Rabbit-New Zealand White anti-Mouse Polyclonal Antibody
Mouse
IHC, WB
Unconjugated
100 µl/$393
ADGRB1 / BAI1 Antibody - Immunohistochemistry of paraffin-embedded Human brain using BAI1 Polyclonal Antibody at dilution of 1:40.
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ADGRB1 / BAI1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ADGRB1 / BAI1 Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer using BAI1 Polyclonal Antibody at dilution of 1:40.
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ADGRB1 / BAI1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ADGRB1 / BAI1 Antibody - Immunohistochemistry-Paraffin: BAI1 Antibody - A. Staining of mouse brain. B. Blocking of staining using control peptide.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Human
IHC, IHC-P
Unconjugated
0.1 ml/$386
ADGRB1 / BAI1 Antibody - Immunohistochemistry-Paraffin: BAI1 Antibody - A. Staining of mouse brain. B. Blocking of staining using control peptide.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Mouse, Human
IHC, IHC-P
Biotin Conjugated
0.1 ml/$416
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).