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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ADD3

adducin 3 (gamma)

Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. While adducins alpha and gamma are ubiquitously expressed, the expression of adducin beta is restricted to brain and hematopoietic tissues. Adducin, originally purified from human erythrocytes, was found to be a heterodimer of adducins alpha and beta. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains. The amino-terminal region is protease resistant and globular in shape, while the carboxy-terminal region is protease sensitive. The latter contains multiple phosphorylation sites for protein kinase C, the binding site for calmodulin, and is required for association with spectrin and actin. Alternatively spliced adducin gamma transcripts encoding different isoforms have been described. The functions of the different isoforms are not known.

Gene Name: adducin 3 (gamma)
Synonyms: ADD3, ADDL, Adducin-like protein 70, Adducin 3 (gamma), Adducin gamma subunit, Gamma-adducin
Target Sequences: NM_016824 NP_058432.1 Q9UEY8

Filtered By: None
Target
ADD3 (25)
Reactivity
Human (25)
Mouse (13)
Rat (13)
Bat (4)
Bovine (9)
Chicken (4)
Chimpanzee (3)
Dog (8)
Gibbon (6)
Guinea pig (6)
Hamster (4)
Horse (5)
Monkey (4)
Orangutan (6)
Pig (4)
Rabbit (4)
Xenopus (4)
Zebrafish (7)
Application
IHC (8)
IHC-P (5)
WB (25)
ELISA (9)
ICC (1)
IF (6)
IP (2)
Peptide-ELISA (2)
Host
rabbit (25)
Isotype
IgG (13)
Clonality
polyclonal pc (25)
Format
AP Conjugated (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (13)
Epitope
aa552-580 (8)
C-Terminus (4)
aa261-310 (4)
400-480 aa, Internal (1)
Internal (1)
Pro452 (1)
aa403-452 (1)
aa431-480 (1)
aa600-650 (1)
aa650-700 (1)
Publications
No (25)
Showing 1-25 of 25 results

ADD3 Antibody (aa261-310) IHC-plus™ LS-B12015
Rabbit Polyclonal to Human ADD3
Human
IF IHC IHC-P WB
Unconjugated
50µg  $485.00
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.

ADD3 Antibody (aa261-310, HRP) LS-C466929
Rabbit Polyclonal to Human ADD3
Zebrafish, Mouse, Dog, Bovine, Rat, Human, Chimpanzee, Orangutan, Gibbon
IF IHC IHC-P WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.

ADD3 Antibody (aa261-310, Biotin) LS-C466927
Rabbit Polyclonal to Human ADD3
Zebrafish, Mouse, Dog, Bovine, Rat, Human, Chimpanzee, Orangutan, Gibbon
IF IHC IHC-P WB
Biotin Conjugated
100µl 1mg/ml  $385.00
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.

ADD3 Antibody (aa261-310, FITC) LS-C466928
Rabbit Polyclonal to Human ADD3
Zebrafish, Mouse, Dog, Bovine, Rat, Human, Chimpanzee, Orangutan, Gibbon
IF IHC IHC-P WB
FITC Conjugated
100µl 1mg/ml  $385.00
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.

ADD3 Antibody (aa431-480) IHC-plus™ LS-B10008
Rabbit Polyclonal (IgG) to Human ADD3
Mouse, Rat, Human
IHC IHC-P Peptide-ELISA WB
Unconjugated
50µl 1mg/ml  $425.00
Anti-ADD3 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Western blot analysis of lysates from HepG2 and 293 cells, using ADD3 Antibody. The lane on the right is blocked with the synthesized peptide.
Anti-ADD3 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Western blot analysis of lysates from HepG2 and 293 cells, using ADD3 Antibody. The lane on the right is blocked with the synthesized peptide.

ADD3 Antibody (400-480 aa, Internal) LS-C381920
Rabbit Polyclonal (IgG) to Human ADD3
Mouse, Rat, Human
ELISA IF IHC WB
Unconjugated
100µl 1mg/ml  $265.00
Western blot of Adducin gamma antibody
Western blot of Adducin gamma antibody
Western blot of Adducin gamma antibody
Western blot of Adducin gamma antibody

ADD3 Antibody (Pro452) LS-C176869
Rabbit Polyclonal to Human ADD3
Mouse, Rat, Human
IF IHC WB
Unconjugated
100µl  $345.00
Western blot of Adducin (P452) pAb in extracts from A549 cells.
Western blot of Adducin (P452) pAb in extracts from A549 cells.

ADD3 Antibody (Internal) LS-C351794
Rabbit Polyclonal to Human ADD3
Mouse, Bovine, Rat, Human
ICC IHC WB
Unconjugated
100µl 1mg/ml  $245.00
Western blot analysis of Gamma-adducin expression in HeLa (A); NIH3T3 (B); H9C2 (C); A375 (D); K562 (E) whole cell lysates.
Western blot analysis of Gamma-adducin expression in HeLa (A); NIH3T3 (B); H9C2 (C); A375 (D); K562 (E) whole cell lysates.

ADD3 Antibody LS-C752074
Rabbit Polyclonal (IgG) to Human ADD3
Human
ELISA WB
Unconjugated
100µg  $335.00

ADD3 Antibody (aa552-580) LS-C319337
Rabbit Polyclonal (IgG) to Human ADD3
Human
ELISA WB
Unconjugated
200µl  $530.00

ADD3 Antibody (aa552-580, Biotin) LS-C250879
Rabbit Polyclonal (IgG) to Human ADD3
Human
ELISA WB
Biotin Conjugated
200µl  $680.00

ADD3 Antibody (aa552-580, FITC) LS-C250880
Rabbit Polyclonal (IgG) to Human ADD3
Human
ELISA WB
FITC Conjugated
200µl  $680.00

ADD3 Antibody (aa552-580, AP) LS-C250877
Rabbit Polyclonal (IgG) to Human ADD3
Human
ELISA WB
AP Conjugated
200µl  $680.00

ADD3 Antibody (aa552-580, APC) LS-C250878
Rabbit Polyclonal (IgG) to Human ADD3
Human
ELISA WB
APC Conjugated
200µl  $680.00

ADD3 Antibody (aa552-580, Azide-free, HRP) LS-C250881
Rabbit Polyclonal (IgG) to Human ADD3
Human
ELISA WB
HRP Conjugated, Azide-free
200µl  $680.00

ADD3 Antibody (aa552-580, PE) LS-C250883
Rabbit Polyclonal (IgG) to Human ADD3
Human
ELISA WB
PE Conjugated
200µl  $680.00

ADD3 Antibody (aa650-700) LS-C290372
Rabbit Polyclonal (IgG) to Human ADD3
Dog, Guinea pig, Bovine, Horse, Human
IP WB
Unconjugated
100µl 1mg/ml  $395.00

ADD3 Antibody (aa600-650) LS-C290369
Rabbit Polyclonal (IgG) to Human ADD3
Guinea pig, Human
IP WB
Unconjugated
100µl 1mg/ml  $395.00

ADD3 Antibody (aa403-452) LS-C200090
Rabbit Polyclonal (IgG) to Human ADD3
Mouse, Rat, Human
Peptide-ELISA WB
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Western blot analysis of the lysates from HT-29 cells using ADD3 antibody.
Western blot analysis of the lysates from HT-29 cells using ADD3 antibody.

ADD3 Antibody (C-Terminus) LS-C135668
Rabbit Polyclonal to Human ADD3
Xenopus, Chicken, Zebrafish, Pig, Horse, Rat, Hamster, Bat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey
WB
Unconjugated
50µg  $365.00
ADD3 antibody Western blot of THP-1 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
ADD3 antibody Western blot of THP-1 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

ADD3 Antibody (C-Terminus, HRP) LS-C466926
Rabbit Polyclonal to Human ADD3
Xenopus, Chicken, Zebrafish, Pig, Horse, Rat, Hamster, Bat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Orangutan
WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
ADD3 antibody Western blot of THP-1 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
ADD3 antibody Western blot of THP-1 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

ADD3 Antibody (C-Terminus, Biotin) LS-C466924
Rabbit Polyclonal to Human ADD3
Xenopus, Chicken, Zebrafish, Pig, Horse, Rat, Hamster, Bat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Orangutan
WB
Biotin Conjugated
100µl 1mg/ml  $385.00
ADD3 antibody Western blot of THP-1 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
ADD3 antibody Western blot of THP-1 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

ADD3 Antibody (C-Terminus, FITC) LS-C466925
Rabbit Polyclonal to Human ADD3
Xenopus, Chicken, Zebrafish, Pig, Horse, Rat, Hamster, Bat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Orangutan
WB
FITC Conjugated
100µl 1mg/ml  $385.00
ADD3 antibody Western blot of THP-1 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
ADD3 antibody Western blot of THP-1 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

ADD3 Antibody (aa552-580) LS-C156080
Rabbit Polyclonal to Human ADD3
Human
WB
Unconjugated
400µl  $305.00
ADD3 Antibody western blot of NCI-H292 cell line lysates (35 ug/lane). The ADD3 antibody detected the ADD3 protein (arrow).
ADD3 Antibody western blot of NCI-H292 cell line lysates (35 ug/lane). The ADD3 antibody detected the ADD3 protein (arrow).

ADD3 Antibody LS-C356814
Rabbit Polyclonal to Human ADD3
Mouse, Rat, Human
WB
Unconjugated
100µl  $305.00
Anti-Gamma-adducin Antibody at 1:1000 dilution + K562 whole cell lysates Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution Predicted band size : 79 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Anti-Gamma-adducin Antibody at 1:1000 dilution + K562 whole cell lysates Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution Predicted band size : 79 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Showing 1-25 of 25 results

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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