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ADCY10 / Adenylate Cyclase 10
adenylate cyclase 10 (soluble)
The protein encoded by this gene belongs to a distinct class of mammalian adenylyl cyclase that is soluble and insensitive to G protein or forskolin regulation. It is thought to function as a general bicarbonate sensor throughout the body. It may also play an important role in the generation of cAMP in spermatozoa, implying possible roles in sperm maturation through the epididymis, capacitation, hypermotility, and/or the acrosome reaction. Genetic variations in this gene are associated with absorptive hypercalciuria type 2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | adenylate cyclase 10 (soluble) |
| Family/Subfamily: | Adenylate cyclase , not assigned-Adenylate cyclase |
| Synonyms: | ADCY10, 3,5-cyclic AMP synthetase, Adenylate cyclase 10 (soluble), Adenylate cyclase homolog, Adenylate cyclase type 10, AH-related protein, HCA2, HsAC, RP1-313L4.2, SAC, ATP pyrophosphate-lyase, SACI, Sacy |
| Target Sequences: | NM_018417 NP_060887.2 Q96PN6 |
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