ADAMTS4

ADAM metallopeptidase with thrombospondin type 1 motif, 4

ADAMTS4 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma.

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Products

Proteins (7)

Type

Over-Expression Lysate (2)

Recombinant (5)

Target

ADAMTS4 (7)

Publications

No (7)

Tag

GST (1)

GST, N-terminus (1)

His (1)

His, N-Terminal (1)

Myc-DDK (Flag) (3)

Species

Human (6)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (2)

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Human ADAMTS4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88793

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

90 kDa

Price:

20 µg/$150

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ADAMTS4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116177

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

90 kDa

Price:

100 µg/$494

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Human ADAMTS4 Protein (Recombinant GST) (Full Length) - LS-G31666

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

62.4 kDa

Price:

2 µg/$439

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Human ADAMTS4 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71108

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

90 kDa

Price:

20 µg/$1,107

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Human ADAMTS4 Protein (Recombinant His, N-Terminal) (Pro47-Thr339) - LS-G97020

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

34 kDa

Price:

10 µg/$265; 100 µg/$365; 50 µg/$315

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Human ADAMTS4 Protein (Recombinant GST, N-terminus) (aa693-802) - LS-G61153

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human ADAMTS4 Protein (Recombinant His) (aa437-575) - LS-G16093

Source:

E. coli

Tag:

His

Molecular Weight:

16.7 kDa

Price:

10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060

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