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ADAM8
ADAM metallopeptidase domain 8
ADAM8 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants.
| Gene Name: | ADAM metallopeptidase domain 8 |
| Family/Subfamily: | Protease , Metallopeptidase M12B |
| Synonyms: | ADAM8, ADAM metallopeptidase domain 8, Cell surface antigen MS2, ADAM 8, MS2, CD156, CD156a antigen |
| Target Sequences: | NM_001109 NP_001100.3 P78325 |
Publications (3)
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