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ADAM2 / Fertilin Beta
ADAM metallopeptidase domain 2
Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein.
| Gene Name: | ADAM metallopeptidase domain 2 |
| Family/Subfamily: | Protease , Metallopeptidase M12B |
| Synonyms: | ADAM2, ADAM 2, CRYN1, CRYN2, CT15, ADAM metallopeptidase domain 2, FTNB, Fertilin, Fertilin beta, Fertilin subunit beta, PH-30, PH-30b, PH30, PH30-beta, Cancer/testis antigen 15 |
| Target Sequences: | NM_001464 NP_001455.3 Q99965 |
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