ADAM17 / TACE

ADAM metallopeptidase domain 17

Tumor-necrosis factor-a is a proinflammatory cytokine and contributes to a variety of inflammatory disease responses and programmed cell death. TNF-a is synthesized as a 26K type II membrane-bound precursor that is cleaved by a convertase to generate secreted 17K mature TNF-a. TNF-a converting enzyme (TACE) protein was recently purified and the human and mouse TACE cDNAs were cloned by several groups separately. TACE is a membrane-bound metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease). TACE also processes other cell surface proteins, including TNF receptor, TGFa, the L-selectin adhesion molecule, and alpha-cleavage of amyloid protein precursor (APP). TACE mRNA is expressed in a variety of human and murine tissues. TACE was selected as one of the few targets in cytokine activation by the Eighth International Conference of the Inflammation Research Association. ADAM17 is a Metallopeptidase M12B type protease.

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ELISA Kits (11)

Type

Custom (1)

Sandwich (10)

Target

ADAM17 / TACE (11)

Reactivity

Human (5)

Mouse (2)

Rat (3)

Pig (1)

Product Group

Coronavirus Detection (11)

ELISA Kits for Associated Targets (11)

Format

96-Well Microplate (3)

96-Well Strip Plate (8)

Publications

No (11)

Sample Type

Cell Culture Supernatants (1)

Cell Lysates (3)

Plasma (6)

Serum (7)

Tissue Homogenates (4)

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Rat ADAM17 / TACE (Sandwich ELISA) ELISA Kit - LS-F22349

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

0.31 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Human ADAM17 / TACE (Sandwich ELISA) ELISA Kit - LS-F23826

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Serum

Price:

1 Plate/$651

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Mouse ADAM17 / TACE (Sandwich ELISA) ELISA Kit - LS-F16862

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Human ADAM17 / TACE (Sandwich ELISA) ELISA Kit - LS-F6383

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$641

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Pig ADAM17 / TACE (Sandwich ELISA) ELISA Kit - LS-F16861

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Pig

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Human ADAM17 / TACE (Sandwich ELISA) ELISA Kit - LS-F188

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

78.15 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$840

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Mouse ADAM17 / TACE (Sandwich ELISA) ELISA Kit - LS-F38989

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$834

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Rat ADAM17 / TACE (Sandwich ELISA) ELISA Kit - LS-F8499

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$856

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Human ADAM17 / TACE (Sandwich ELISA) ELISA Kit - LS-F33673

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Rat ADAM17 / TACE (Custom ELISA) ELISA Kit - LS-F16860

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

Select

Human ADAM17 / TACE (Sandwich ELISA) ELISA Kit - LS-F10739

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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