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ADAM11
ADAM metallopeptidase domain 11
ADAM11 is a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene represents a candidate tumor suppressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping.
| Gene Name: | ADAM metallopeptidase domain 11 |
| Family/Subfamily: | Protease Non Catalytic , Metallopeptidase Non-catalytic |
| Synonyms: | ADAM11, ADAM 11, MDC |
| Target Sequences: | NM_002390 NP_002381.2 O75078 |
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